Evidence map›Paper›PMID 27796497›Full record

ArticleInternational journal of colorectal disease2017

Postoperative recurrence and risk factors of colorectal cancer perforation.

Hiroshi Asano, Kazuto Kojima, Naomi Ogino, Hiroyuki Fukano, Yasuhiro Ohara, Nozomi Shinozuka

Abstract read
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In one paragraph

Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  19. The Bucharest ESTES consensus statement on peritonitis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroshi AsanoDepartment of General Surgery, Saitama Medical University, 38 Morohongou, Moroyama, Irumagun, Saitama, 350-0495, Japan. hiroshia@saitama-med.ac.jp.ORCID http://orcid.org/0000-0002-5867-8899
Kazuto KojimaDepartment of General Surgery, Saitama Medical University, 38 Morohongou, Moroyama, Irumagun, Saitama, 350-0495, Japan.
Naomi OginoDepartment of General Surgery, Saitama Medical University, 38 Morohongou, Moroyama, Irumagun, Saitama, 350-0495, Japan.
Hiroyuki FukanoDepartment of General Surgery, Saitama Medical University, 38 Morohongou, Moroyama, Irumagun, Saitama, 350-0495, Japan.
Yasuhiro OharaDepartment of General Surgery, Saitama Medical University, 38 Morohongou, Moroyama, Irumagun, Saitama, 350-0495, Japan.
Nozomi ShinozukaDepartment of General Surgery, Saitama Medical University, 38 Morohongou, Moroyama, Irumagun, Saitama, 350-0495, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe common causes of colorectal perforation are benign. However, perforated colorectal cancer confers a risk of recurrence in the long term because of the malignant nature of the disease. In addition, the recurrence rate can also increase because of dissemination of cancer cells, reduced extent of lymph node dissection to prioritize saving life, and other reasons.

methodsWe evaluated the clinical features and postoperative recurrence in patients with perforated colorectal cancer who developed general peritonitis and underwent emergency surgery during a 7-year period between April 2007 and March 2014.

resultsDuring the study period, 44 patients had colorectal cancer perforation. The cancer sites were the ascending colon in 6 patients, transverse colon in 1, descending colon in 4, sigmoid colon in 15, and rectum in 18. The disease stage was stage II in 18 patients, stage III in 15, and stage IV in 7. Among 22 patients who could be followed up, 8 had postoperative recurrence. The recurrence rates were 18.2% for stage II cancer and 54.5% for stage III. Postoperative recurrence was more likely to occur in the patients positive for lymph node metastasis, those with poorly differentiated adenocarcinoma, those with T4 cancer, and those who did not receive postoperative adjuvant chemotherapy.

conclusionThe recurrence rate was higher in the patients with perforated colorectal cancer than in those who underwent surgery for common colorectal cancer. The prognosis can be expected to improve by performing standard surgical procedures, to the maximum extent possible, followed by postoperative adjuvant chemotherapy.

Indexed as

Postoperative CareAgedAged, 80 and overColorectal NeoplasmsFemaleHumansIntestinal PerforationMaleMiddle AgedNeoplasm StagingRecurrenceRisk FactorsAdjuvant chemotherapyColorectal cancerColorectal perforationRecurrence

Identifiers

PMID27796497

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.