Evidence map›Paper›PMID 27796484›Full record

ArticleInternational orthopaedics2017

Reamed intramedullary exchange nailing in the operative treatment of aseptic tibial shaft nonunion.

Christian Hierholzer, Jan Friederichs, Claudio Glowalla, Alexander Woltmann, Volker Bühren, Christian von Rüden

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Interface stability of intramedullary nail locking configurations under combined axial and torsional loading.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  3. Article
  4. Article
  5. Circulating CD38Scientific reports · 2026
    Article
  6. [Non-Unions of the lower extremities].Chirurgie (Heidelberg, Germany) · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. [Infected nonunion: diagnostic and therapeutic work-up].Unfallchirurgie (Heidelberg, Germany) · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Nonunions of the humerus - Treatment concepts and results of the last five years.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2019
    Article
  17. Review
  18. Article
  19. Review
  20. [Pseudarthroses of the long bones].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Christian HierholzerDepartment of Trauma Surgery, University Hospital Zurich, Zurich, Switzerland.
Jan FriederichsDepartment of Trauma Surgery, Trauma Center Murnau, Professor Küntscher Str. 8, 82418 Murnau, Germany.
Claudio GlowallaClinic of Orthopedics and Sports Orthopedics, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Alexander WoltmannDepartment of Trauma Surgery, Trauma Center Murnau, Professor Küntscher Str. 8, 82418 Murnau, Germany.
Volker BührenDepartment of Trauma Surgery, Trauma Center Murnau, Professor Küntscher Str. 8, 82418 Murnau, Germany.
Christian von RüdenDepartment of Trauma Surgery, Trauma Center Murnau, Professor Küntscher Str. 8, 82418 Murnau, Germany. christian.vonrueden@bgu-murnau.de.
Berufsgenossenschaftliche Unfallklinik Murnau · DETechnical University of Munich · DEUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate a standardized treatment protocol regarding the rate of secondary bone union, complications, and functional outcome.

methodsThis study was started as a prospective study in a single Level I Trauma Centre between 2003 and 2012. The study group consisted of 188 patients with the diagnosis of an aseptic tibial shaft nonunion. Exchange nailing was performed following a standardized surgical protocol. Long-term follow-up was analyzed for rate of bone healing and functional outcome.

resultsOsseous healing was achieved in 182 out of 188 patients (97 %). In 165 out of 188 patients (88 %), bone healing was observed timely and uneventfully after a single exchange nailing procedure. An open approach was necessary in 32 patients (17 %). Twenty-three patients (12 %) required additional therapy such as extracorporeal shock wave therapy. Post-operative complications were observed in seven patients (4 %). Almost all patients demonstrated osseous healing within 12 months, with the majority of osseous healing occurring within six months. A relevant shortening of the fractured tibia was observed in 20 out of 188 patients (11 %). After a median follow-up of 23 months (range 12-45 months), outcome was evaluated using the assessment system of Friedman/Wyman. In summary, 154 out of 188 patients (82 %) had a good functional long-term result. DISCUSSION: Reamed intramedullary exchange nailing including correction of axis alignment is a safe and effective treatment of aseptic tibial shaft nonunion with a high rate of bone healing and a good radiological and functional long-term outcome.

Indexed as

Bone NailsAdolescentAdultAgedAged, 80 and overClinical ProtocolsFemaleFracture Fixation, IntramedullaryFracture HealingFractures, UnunitedHumansMaleMiddle AgedProspective StudiesRecovery of FunctionReoperationLong-term outcomeNonunionReamed intramedullary exchange nailingTibia

Identifiers

PMID27796484
OpenAlexW2543788406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.