Evidence map›Paper›PMID 27796014›Full record

ArticleProceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data

An Interactive Learning Framework for Scalable Classification of Pathology Images.

Michael Nalisnik, David A Gutman, Jun Kong, Lee Ad Cooper

Open access · greenAbstract read
In one paragraph

Article in Proceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. TissueWand, a Rapid Histopathology Annotation Tool.Journal of pathology informatics · 2020
    Article
  3. Comparison of Different Classifiers with Active Learning to Support Quality Control in Nucleus Segmentation in Pathology Images.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2018
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michael NalisnikDepartment of Computer Science and Mathematics, Emory University, Emory University School of Medicine, Atlanta, GA 30322.
David A GutmanDepartment of Neurology, Emory University, Emory University School of Medicine, Atlanta, GA 30322; Winship Cancer Institute, Emory University, Emory University School of Medicine, Atlanta, GA 30322.
Jun KongDepartments of Biomedical Informatics, Emory University School of Medicine/Georgia Institute of Technology, Atlanta, GA 30322.
Lee Ad CooperDepartments of Biomedical Informatics, Emory University School of Medicine/Georgia Institute of Technology, Atlanta, GA 30322; Department of Biomedical Engineering, Emory University School of Medicine/Georgia Institute of Technology, Atlanta, GA 30322; Winship Cancer Institute, Emory University School of Medicine/Georgia Institute of Technology, Atlanta, GA 30322.
Emory University · USGeorgia Institute of Technology · US

Funding

Advanced Development of an Open-source Platform for Web-based Integrative Digital Image Analysis in CancerU24CA194362 · NCI · EMORY UNIVERSITY · PI COOPER, LEE, GUTMAN, DAVID ANDREW · 2015 to 2019
$3.6M
Quantitative Analysis of GBM Invasion Mechanisms with New Imaging ProtocolK25CA181503 · NCI · GEORGIA STATE UNIVERSITY · PI KONG, JUN · 2014 to 2018
$592k
Multiscale Framework for Molecular Heterogeneity AnalysisK22LM011576 · NLM · EMORY UNIVERSITY · PI COOPER, LEE · 2013 to 2015
$485k
NCI NIH HHS K25 CA181503NCI NIH HHS U24 CA194362NLM NIH HHS K22 LM011576
6 · The paper itself

Abstract

Recent advances in microscopy imaging and genomics have created an explosion of patient data in the pathology domain. Whole-slide images (WSIs) of tissues can now capture disease processes as they unfold in high resolution, recording the visual cues that have been the basis of pathologic diagnosis for over a century. Each WSI contains billions of pixels and up to a million or more microanatomic objects whose appearances hold important prognostic information. Computational image analysis enables the mining of massive WSI datasets to extract quantitative morphologic features describing the visual qualities of patient tissues. When combined with genomic and clinical variables, this quantitative information provides scientists and clinicians with insights into disease biology and patient outcomes. To facilitate interaction with this rich resource, we have developed a web-based machine-learning framework that enables users to rapidly build classifiers using an intuitive active learning process that minimizes data labeling effort. In this paper we describe the architecture and design of this system, and demonstrate its effectiveness through quantification of glioma brain tumors.

Indexed as

biomedical image processinginteractive systemsmachine learningpathology

Identifiers

PMID27796014
PMCPMC5082843
OpenAlexW2201011793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.