Evidence map›Paper›PMID 27795938›Full record

ArticleCurrent hepatology reports2016

Noninvasive Markers of Fibrosis and Inflammation in Nonalcoholic Fatty Liver Disease.

Saumya Jayakumar, Stephen A Harrison, Rohit Loomba

Open access · greenAbstract read
In one paragraph

Article in Current hepatology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Current Modalities of Fibrosis Assessment in Non-alcoholic Fatty Liver Disease.Journal of clinical and translational hepatology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Saumya JayakumarDivision of Gastroenterology and Hepatology, University of Calgary, San Antonio, Texas.
Stephen A HarrisonBrook Army Medical Center, San Antonio, Texas.
Rohit LoombaNAFLD Research Center, University of California, San Diego; Division of Gastroenterology, University of California, San Diego; Division of Epidemiology, University of California, San Diego.
University of Calgary · CAUniversity of California, San Diego · US

Funding

GENETIC EPIDEMIOLOGY OF NONALCOHOLIC FATTY LIVER DISEASEK23DK090303 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LOOMBA, ROHIT · 2011 to 2014
$721k
NIDDK NIH HHS K23 DK090303
6 · The paper itself

Abstract

The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Nonalcoholic steatohepatitis (NASH) and fibrosis are associated with elevated morbidity and mortality, and a means of differentiating these diseases from simple steatosis (SS) is needed. Liver biopsy in all patients with NAFLD is not feasible, thus necessitating a noninvasive method for discerning the presence of inflammation and fibrosis. Of the various serum markers, cytokeratin-18 seems to best predict NASH, the NAFLD Fibrosis Score is most closely correlated with fibrosis, and transient elastography can be used for diagnosis of cirrhosis, or to exclude cirrhosis, although its utility is limited by obesity.

Indexed as

biomarkersfibrosisinflammationmagnetic resonance elastographymagnetic resonance imaging (MRI)nonalcoholic fatty liver disease (NAFLD)nonalcoholic steatohepatitis (NASH)noninvasive markersproton-density-fat-fractiontransient elastography

Identifiers

PMID27795938
PMCPMC5081215
OpenAlexW2336943481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.