Evidence map›Paper›PMID 27795872›Full record

ArticleJournal of pulmonary & respiratory medicine2014

The Protective Effect of Hispanic Ethnicity on Chronic Obstructive Pulmonary Disease Mortality is Mitigated by Smoking Behavior.

Gregory L Kinney, Deborah Sk Thomas, Lisa Cicutto, Lee S Newman, Sharon Lutz, John E Hokanson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of pulmonary & respiratory medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Chronic Obstructive Pulmonary Disease in Hispanics. A 9-Year Update.American journal of respiratory and critical care medicine · 2018
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gregory L KinneyDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora Colorado, USA.
Deborah Sk ThomasDepartment of Geography and Environmental Sciences, University of Colorado Denver, Denver Colorado, USA.
Lisa CicuttoNational Jewish Hospital and University of Colorado Denver, Denver Colorado, USA.
Lee S NewmanDepartment of Environmental Health, Colorado School of Public Health, University of Colorado Denver, Aurora Colorado, USA.
Sharon LutzDepartment of Biostatistics, Colorado School of Public Health, University of Colorado Denver, Aurora Colorado, USA.
John E HokansonDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora Colorado, USA.
Colorado School of Public Health · US

Funding

ZOPOLRESTAT PHARMACOKINETICS IN DIABETICS WITH VARYING RENAL FUNCTIONM01RR000051 · NCRR · UNIVERSITY OF COLORADO DENVER · PI KOSMISKI, LISA A. · 1985 to 2008
$52.6M
DIABETES MELLITUS IN THE SAN LUIS VALLEY, COLORADOR01DK030747 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI HAMMAN, RICHARD F · 1986 to 1998
–
NCRR NIH HHS M01 RR000051NIDDK NIH HHS R01 DK030747
6 · The paper itself

Abstract

rationaleStudies in Hispanic/Latino populations have shown ethnicity to be either a predictive or protective factor for COPD mortality and it is unclear whether this disagreement is attributable to ethnic differences in smoking rates, smoking behavior or differences in genetic susceptibility.

objectivesThis study will examine the role of smoking behavior as a means of explaining differences in risk for COPD mortality between Hispanics and non-Hispanic whites.

methodsParticipants were recruited into a cohort study from the San Luis Valley in Colorado beginning in the early 1980's and followed for mortality until 2012. COPD and cardiovascular disease are often comorbid conditions and account for the competing risk of CVD in the analysis of COPD mortality. Mortality searches were conducted regularly and all ICD codes were collected for mortality event. Primary and secondary causes of each event were assessed using appropriate codes.

resultsHispanic current smokers did not differ from NHW current smokers in years smoked (p=0.6) but Hispanic former smokers accumulated more years smoked compared to NHW former smokers (22 vs. 20, p=0.047). Hispanic ethnicity was significantly protective for COPD mortality adjusting for age, gender, pre-existing emphysema, hypertension and smoking status and accounting for the effect of CVD mortality (RR=0.58, 95% C.I. 0.34-0.99, p=0.035). Further adjustment for smoking behavior mitigated this effect.

conclusionsThe lower COPD mortality seen in Hispanic smokers may be due lower cumulative exposure to tobacco smoke. Thus, smoking behavior may play a key role in explaining differences in COPD mortality as they relate to Hispanic ethnicity.

Indexed as

Cardiovascular Disease (CVD)Chronic obstructive pulmonary diseaseInternational classification of diseaseSmoking

Identifiers

PMID27795872
PMCPMC5082977
OpenAlexW2318747201

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.