Epigenetics of Ancient DNA.

S V Zhenilo, A S Sokolov, E B Prokhortchouk

Open access · bronzeAbstract read

In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 91% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

DNA Methyltransferases: From Evolution to Clinical Applications.International journal of molecular sciences · 2022
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

S V ZheniloInstitute of Bioengineering, Federal Research Center "Fundamentals of Biotechnology", Russian Academy of Sciences, prospect 60-letiya Oktyabrya, Str. 7/1, Moscow, 117312, Russia.

A S SokolovInstitute of Bioengineering, Federal Research Center "Fundamentals of Biotechnology", Russian Academy of Sciences, prospect 60-letiya Oktyabrya, Str. 7/1, Moscow, 117312, Russia.

E B ProkhortchoukInstitute of Bioengineering, Federal Research Center "Fundamentals of Biotechnology", Russian Academy of Sciences, prospect 60-letiya Oktyabrya, Str. 7/1, Moscow, 117312, Russia.

Federal Center Research Fundamentals of Biotechnology · RURussian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initially, the study of DNA isolated from ancient specimens had been based on the analysis of the primary nucleotide sequence. This approach has allowed researchers to study the evolutionary changes that occur in different populations and determine the influence of the environment on genetic selection. However, the improvement of methodological approaches to genome-wide analysis has opened up new possibilities in the search for the epigenetic mechanisms involved in the regulation of gene expression. It was discovered recently that the methylation status of the regulatory elements of the

Indexed as

ancient DNADNA methylationepigenetics

Identifiers

PMID27795845

PMCPMC5081710

OpenAlexW2548185323

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.