ArticleJournal of pharmaceutical policy and practice2016
Impact of switching from intravenous to oral linezolid therapy in Japanese patients: a retrospective cohort study.
Article in Journal of pharmaceutical policy and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Transitioning to oral therapy compared to IV inAnnals of medicine and surgery (2012) · 2025Article
- Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study.SAGE open medicine · 2022Article
- Prescribing Pattern of Antibiotics Using WHO Prescribing Indicators Among Inpatients in Ethiopia: A Need for Antibiotic Stewardship Program.Infection and drug resistance · 2020Article
- Assessment of inpatient antibiotic use in Halibet National Referral Hospital using WHO indicators: a retrospective study.BMC research notes · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh oral bioavailability of antimicrobial agents can result in the replacement of intravenous (IV) therapy with oral therapy when a patient meets defined clinical criteria. However, few studies have evaluated the effects of switching antibiotic administration route in Japan, especially for linezolid. This study evaluated an IV-to-oral antibiotic switching program for linezolid treatment at a university hospital in Japan.
methodsIn a retrospective cohort study of 73 patients, we assessed the efficacy and safety of IV-to-oral linezolid therapy (
resultsDuration of linezolid treatment, changes in C-reactive protein or platelet count from baseline, re-administration of anti-methicillin-resistant
conclusionsAn IV-to-oral switching program could reduce the duration of IV linezolid therapy without worsening clinical outcomes in Japanese patients receiving linezolid therapy.
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Registered trials
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