Evidence map›Paper›PMID 27795748›Full record

ArticleBiomicrofluidics2016

A bilayer small diameter

David M Hoganson, Eric B Finkelstein, Gwen E Owens, James C Hsiao, Kurt Y Eng, Katherine M Kulig, Ernest S Kim, Tatiana Kniazeva, Irina Pomerantseva, Craig M Neville and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Eric B FinkelsteinSyracuse Biomaterials Institute and Department of Biomedical and Chemical Engineering, Syracuse University , Syracuse, New York 13244, USA.
Gwen E OwensCenter for Regenerative Medicine, Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts 02114, USA.
James C HsiaoDraper Laboratories , Cambridge, Massachusetts 02139, USA.
Kurt Y EngPfizer Inc. , Cambridge, Massachusetts 02139, USA.ORCID 0000-0002-6445-4891
Katherine M KuligCenter for Regenerative Medicine, Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts 02114, USA.
Ernest S KimDraper Laboratories , Cambridge, Massachusetts 02139, USA.
Tatiana KniazevaDraper Laboratories , Cambridge, Massachusetts 02139, USA.
Irina PomerantsevaCenter for Regenerative Medicine, Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts 02114, USA.
Craig M NevilleCenter for Regenerative Medicine, Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts 02114, USA.
James R TurkAmgen , Thousand Oaks, California 91320, USA.
Bernard FerminiPfizer Inc. , Groton, Connecticut 06340, USA.
Jeffrey T BorensteinDraper Laboratories , Cambridge, Massachusetts 02139, USA.
Joseph P VacantiCenter for Regenerative Medicine, Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts 02114, USA.
Boston Children's Hospital · US

Funding

Biliary morphogenesis and bile canaliculi integrationF32DK076349 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI HOGANSON, DAVID · 2006 to 2007
$99k
NIDDK NIH HHS F32 DK076349
6 · The paper itself

Abstract

In pre-clinical safety studies, drug-induced vascular injury (DIVI) is defined as an adverse response to a drug characterized by degenerative and hyperplastic changes of endothelial cells and vascular smooth muscle cells. Inflammation may also be seen, along with extravasation of red blood cells into the smooth muscle layer (i.e., hemorrhage). Drugs that cause DIVI are often discontinued from development after considerable cost has occurred. An

Identifiers

PMID27795748
PMCPMC5065573
OpenAlexW2530552271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.