Evidence map›Paper›PMID 27795667›Full record

ArticleEnvironmental health insights2016

Chronic Ethanol Exposure Effects on Vitamin D Levels Among Subjects with Alcohol Use Disorder.

Olalekan Ogunsakin, Tete Hottor, Ashish Mehta, Maureen Lichtveld, Michael McCaskill

Open access · goldAbstract read
In one paragraph

Article in Environmental health insights, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. HeterozygousFrontiers in physiology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Single Nucleotide Polymorphisms in the Vitamin D Receptor Gene (International journal of molecular sciences · 2018
    Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Olalekan OgunsakinDepartment of Global Environmental Health Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Tete HottorDepartment of Global Environmental Health Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Ashish MehtaEmory University School of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Atlanta, GA, USA.; Atlanta VA Medical Center, Atlanta, GA, USA.
Maureen LichtveldDepartment of Global Environmental Health Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Michael McCaskillDepartment of Global Environmental Health Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Tulane University · USAtlanta Medical Center · US

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Supplement: CoPARC: Colorado Pulmonary Alcohol Research CollaborativeR24AA019661 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM · 2011 to 2026
$8.5M
Ethanol-induced dysfunction of lung anti-microbial activity via vitamin D modulatK01HL121041 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI MCCASKILL, MICHAEL L · 2014 to 2018
$689k
Alcohol abuse, oxidative stress, and zinc deficiency in lung diseaseIK2CX000643 · VA · VETERANS HEALTH ADMINISTRATION · PI MEHTA, ASHISH J · 2013 to 2017
–
CSRD VA IK2 CX000643NCATS NIH HHS UL1 TR001082NHLBI NIH HHS K01 HL121041NIAAA NIH HHS R24 AA019661
6 · The paper itself

Abstract

Vitamin D has been previously recognized to play important roles in human immune system and function. In the pulmonary system, vitamin D regulates the function of antimicrobial peptides, especially cathelicidin/LL-37. Human cathelicidin/LL-37 is a bactericidal, bacteriostatic, and antiviral endogenous peptide with protective immune functions. Chronic exposure to excessive alcohol has the potential to reduce levels of vitamin D (inactive vitamin D [25(OH)D

Indexed as

cathelicidinCYP27B1CYP2E1Excessive ethanolpneumoniavitamin D

Identifiers

PMID27795667
PMCPMC5074581
OpenAlexW2538823874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.