Evidence map›Paper›PMID 27794521›Full record

ReviewInternational journal of epidemiology2016

Quantitative in vivo neurochemical profiling in humans: where are we now?

Jessica McKay, Ivan Tkáč

Open access · bronzeAbstract readReview
In one paragraph

Review in International journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. General technical remarks onPolish journal of radiology · 2019
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Brain Edema in Chronic Hepatic Encephalopathy.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jessica McKayCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA.
Ivan TkáčCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA ivan@cmrr.umn.edu.
Resonance Research (United States) · US

Funding

NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
NIBIB NIH HHS P41 EB015894NINDS NIH HHS P30 NS076408
6 · The paper itself

Abstract

Proton nuclear magnetic resonance spectroscopy of biofluids has become one of the key techniques for metabolic profiling and phenotyping. This technique has been widely used in a number of epidemiological studies and in a variety of health disorders. However, its utilization in brain disorders is limited due to the blood-brain barrier, which not only protects the brain from unwanted substances in the blood, but also substantially limits the potential of finding biomarkers for neurological disorders in serum. This review article focuses on the potential of localized in vivo proton magnetic resonance spectroscopy (

Indexed as

Proton Magnetic Resonance SpectroscopyBiomarkersBrainHumansNervous System DiseasesNeurochemistryBiomarkers1H-MRSCNS disordersmethodologyneurochemical profilingspectral quality

Identifiers

PMID27794521
PMCPMC5100624
OpenAlexW2545478211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.