Evidence map›Paper›PMID 27793996›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2016

Lin28b Regulates Fetal Regulatory T Cell Differentiation through Modulation of TGF-β Signaling.

Yelena Bronevetsky, Trevor D Burt, Joseph M McCune

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Regulation of HSC development and function by Lin28b.Frontiers in cell and developmental biology · 2025
    Review
  7. Review
  8. Review
  9. Downregulation ofeLife · 2024
    Article
  10. Downregulation ofbioRxiv : the preprint server for biology · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yelena BronevetskyDivision of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94110; yelena.bronevetsky@gmail.com.ORCID 0000-0002-2137-3397
Trevor D BurtDivision of Neonatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94110; and.
Joseph M McCuneDivision of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94110.ORCID 0000-0002-9388-070X
University of California, San Francisco · US

Funding

MOLECULAR AND CELLULAR IMMUNOLOGYT32AI007334 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 1988 to 2023
$11.0M
Layering of the human immune system, viral infections, and childhood asthmaR01AI100082 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCCUNE, JOSEPH M · 2012 to 2016
$1.9M
Human immune system layering and the neonatal response to vaccinesR21AI094009 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCCUNE, JOSEPH M · 2011 to 2012
$425k
NIAID NIH HHS R01 AI100082NIAID NIH HHS R21 AI094009NIAID NIH HHS T32 AI007334
6 · The paper itself

Abstract

Immune tolerance between the fetus and mother represents an active process by which the developing fetus must not mount immune responses to noninherited Ags on chimeric maternal cells that reside in fetal tissue. This is, in part, mediated by the suppressive influence of CD4

Indexed as

CD3 ComplexCell DifferentiationFemaleFetusGene Expression Regulation, DevelopmentalHumansMaleMicroRNAsProtein Serine-Threonine KinasesReceptors, Antigen, T-CellReceptors, Transforming Growth Factor betaReceptor, Transforming Growth Factor-beta Type IReceptor, Transforming Growth Factor-beta Type IIRNA-Binding ProteinsSignal TransductionSmad2 ProteinCD3 ComplexLIN28B protein, humanMicroRNAsmirnlet7 microRNA, humanProtein Serine-Threonine KinasesReceptors, Antigen, T-CellReceptors, Transforming Growth Factor betaReceptor, Transforming Growth Factor-beta Type IReceptor, Transforming Growth Factor-beta Type IIRNA-Binding ProteinsSmad2 ProteinSMAD2 protein, humanTransforming Growth Factor beta

Identifiers

PMID27793996
PMCPMC5123822
OpenAlexW2543937724

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.