Observational studyThe journals of gerontology. Series A, Biological sciences and medical sciences2017
Impact of Underlying Conditions on Zoster-Related Pain and on Quality of Life Following Zoster.
Observational study in The journals of gerontology. Series A, Biological sciences and medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- A prospective randomized comparison of the efficacy of standard antiviral therapy versus ultrasound-guided thoracic paravertebral block for acute herpes zoster.Annals of medicine · 2022Trial
- Herpes Zoster in Aging Patients: Risk Factors and Prevention Strategies.International journal of general medicine · 2026Review
- An Exploratory Investigation of Representations of Herpes Zoster and Adjuvanted Recombinant Herpes Zoster Vaccination in a Sample of Fragile Adults in Italy.Pathogens (Basel, Switzerland) · 2025Article
- Exploring the Link Between Diabetes, Herpes Zoster, and Post-Herpetic Neuralgia: Insights From Mendelian Randomization.Journal of pain research · 2025Article
- Anti-Herpes Zoster Vaccination of Fragile Patients in Hospital Setting: A Nudge Intervention in Italy.Vaccines · 2024Article
- A Prognostic Model Incorporating Relevant Peripheral Blood Inflammation Indicator to Predict Postherpetic Neuralgia in Patients with Acute Herpes Zoster.Journal of pain research · 2024Article
- Impact of Type 1 Versus Type 2 Diabetes on Developing Herpes Zoster and Post-herpetic Neuralgia: A Population-based Cohort Study.Acta dermato-venereologica · 2023Article
- Opioids Prescribing Among Patients with Zoster-Related Pain in Real-Life: A Retrospective, Cohort Study Based on the Clinical Database.Journal of pain research · 2023Article
- Patient-reported quality of life in patients suffering from acute herpes zoster-a systematic review with meta-analysis.British journal of pain · 2022Article
- Herpes zoster risk and burden of disease in immunocompromised populations: a population-based study using health system integrated databases, 2009-2014.BMC infectious diseases · 2020Article
- Incidence of herpes zoster and postherpetic neuralgia in Italian adults aged ≥50 years: A prospective study.Preventive medicine reports · 2019Article
- Measuring herpes zoster disease burden in São Paulo, Brazil: a clinico-epidemiological single-center study.Clinics (Sao Paulo, Brazil) · 2018Observational
- Risk and impact of herpes zoster among COPD patients: a population-based study, 2009-2014.BMC infectious diseases · 2018Article
- Herpes Zoster and Diabetes Mellitus: A Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2018Review
- Epidemiology and long-term disease burden of herpes zoster and postherpetic neuralgia in Taiwan: a population-based, propensity score-matched cohort study.BMC public health · 2018Article
- Varicella-zoster virus infection: a review about varicella and herpes zoster.Anais brasileiros de dermatologiaReview
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic conditions have been investigated as risk factors for developing zoster, but in patients suffering from zoster, the impact of underlying conditions in zoster-related pain and quality of life (QOL) remains unclear.
methodsWe performed a post hoc analysis of a prospective cohort study in immunocompetent zoster patients aged 50 years or older, conducted by general practitioners in Italy between 2009 and 2010. Zoster symptoms, pain intensity and characteristics, and physical and mental health scores were assessed at baseline (zoster diagnosis) and at 1, 3, and 6 months of follow-up.
resultsAmong 413 patients enrolled in the study, 73% (303/413) suffered from underlying conditions of which 69% (209/303) were aged 65 or older. Cardiovascular diseases (75%), diabetes (24%), and respiratory diseases (17%) were most frequent. One to three months after onset, zoster patients with underlying conditions experienced more intense zoster-related pain than those without. QOL scores were significantly lower in patients with underlying conditions, and age-adjusted difference in QOL scores between the groups increased over time, demonstrating a slower recovery for patients with underlying conditions.
conclusionsIn addition to age, the main risk factor of zoster occurrence and severity, the presence of underlying conditions results in more painful and impactful zoster episodes, creating a significant burden for these patients.
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