Evidence map›Paper›PMID 27793853›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2017

Investigating the extremes of the continuum of paracrine functions in CD34-/CD31+ CACs across diverse populations.

Rian Q Landers-Ramos, Ryan M Sapp, Emily VandeWater, Jennifer Macko, Shawn Robinson, Yan Wang, Eva R Chin, Espen E Spangenburg, Steven J Prior, James M Hagberg

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Guidelines for authors and reviewers on antibody use in physiology studies.American journal of physiology. Heart and circulatory physiology · 2018
    Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Exercise and Cardiovascular Progenitor Cells.Comprehensive Physiology · 2019
    Review
  10. Statistical considerations in reporting cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rian Q Landers-RamosDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland.ORCID http://orcid.org/0000-0002-3092-2538
Ryan M SappDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland.
Emily VandeWaterDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland.
Jennifer MackoDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland.
Shawn RobinsonBaltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Yan WangProteomics Core Facility, College of Computer, Mathematics, and Natural Sciences, University of Maryland, College Park, Maryland; and.
Eva R ChinDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland.
Espen E SpangenburgDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland.
Steven J PriorUniversity of Maryland School of Medicine and Baltimore Veterans Affairs Geriatric Research, Education and Clinical Center, Baltimore, Maryland.ORCID http://orcid.org/0000-0002-4627-6489
James M HagbergDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland; hagberg@umd.edu.
University of Maryland, College Park · USUniversity of Maryland, Baltimore · USVeterans Health Administration · US

Funding

Vascular Biology Training ProgramT32HL007698 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Rosemary A Kozar, Dudley K. Strickland · 1991 to 2026
$8.7M
Orbitrap Fusion Tribrid Mass SpectrometerS10OD019938 · OD · UNIV OF MARYLAND, COLLEGE PARK · PI FENSELAU, CATHERINE C · 2015 to 2015
$600k
Effects of Aerobic Exerise on EPCs and Vascular Dysfunction in Aging and T2DMK23AG040775 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI PRIOR, STEVEN J · 2012 to 2014
$532k
NHLBI NIH HHS T32 HL007698NIA NIH HHS K23 AG040775NIH HHS S10 OD019938
6 · The paper itself

Abstract

Paracrine function of circulating angiogenic cells (CACs) is thought to contribute to vascular maintenance. We previously identified S100A8 and S100A9 secreted from physically inactive individuals' CD34 NEW & NOTEWORTHY: S100A8 and S100A9 proteins in concentrations secreted by CD34

Indexed as

Paracrine CommunicationAdolescentAdultAgedAged, 80 and overAntigens, CD34Blotting, WesternCalgranulin ACalgranulin BCapillariesCase-Control StudiesCells, CulturedEndothelial Progenitor CellsHumansHuman Umbilical Vein Endothelial CellsImmunomagnetic SeparationAntigens, CD34Calgranulin ACalgranulin BPlatelet Endothelial Cell Adhesion Molecule-1TLR4 protein, humanToll-Like Receptor 4angiogenesiscirculating angiogenic cellsendothelial cellsmyocardial infarctionparacrine function

Identifiers

PMID27793853
PMCPMC5283912
OpenAlexW2545021348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.