Evidence map›Paper›PMID 27793789›Full record

ArticleNanomedicine : nanotechnology, biology, and medicine2017

Inhibition of Candida albicans biofilm by pure selenium nanoparticles synthesized by pulsed laser ablation in liquids.

Grégory Guisbiers, Humberto H Lara, Ruben Mendoza-Cruz, Guillermo Naranjo, Brandy A Vincent, Xomalin G Peralta, Kelly L Nash

Open access · greenAbstract read
In one paragraph

Article in Nanomedicine : nanotechnology, biology, and medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 102 citations in OpenAlex.

  1. Review
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  10. Antifungal and antibiofilm effects of probioticFrontiers in cellular and infection microbiology · 2024
    Article
  11. Review
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  18. Review
  19. Selenium nanoparticles fromSaudi journal of biological sciences · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Grégory GuisbiersThe University of Texas at San Antonio, Department of Physics and Astronomy, One UTSA Circle, San Antonio, TX, USA. Electronic address: gregory.guisbiers@utsa.edu.
Humberto H LaraThe University of Texas at San Antonio, Department of Physics and Astronomy, One UTSA Circle, San Antonio, TX, USA. Electronic address: humberto.laravillegas@utsa.edu.
Ruben Mendoza-CruzThe University of Texas at San Antonio, Department of Physics and Astronomy, One UTSA Circle, San Antonio, TX, USA.
Guillermo NaranjoThe University of Texas at San Antonio, Department of Physics and Astronomy, One UTSA Circle, San Antonio, TX, USA.
Brandy A VincentThe University of Texas at San Antonio, Department of Physics and Astronomy, One UTSA Circle, San Antonio, TX, USA.
Xomalin G PeraltaThe University of Texas at San Antonio, Department of Physics and Astronomy, One UTSA Circle, San Antonio, TX, USA.
Kelly L NashThe University of Texas at San Antonio, Department of Physics and Astronomy, One UTSA Circle, San Antonio, TX, USA.
The University of Texas at San Antonio · US

Funding

UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
RCMI Center for Interdiscplinary Health Research CIHRG12MD007591 · NIMHD · UNIVERSITY OF TEXAS SAN ANTONIO · PI PERRY, GEORGE · 2012 to 2016
$10.4M
UTSA Maximizing Access to Research Careers Research Training Program - Admin SupplementT34GM007717 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 1985 to 2021
$9.5M
NIGMS NIH HHS R25 GM060655NIGMS NIH HHS T34 GM007717NIMHD NIH HHS G12 MD007591
6 · The paper itself

Abstract

Selenoproteins play an important role in the human body by accomplishing essential biological functions like oxido-reductions, antioxidant defense, thyroid hormone metabolism and immune response; therefore, the possibility to synthesize selenium nanoparticles free of any contaminants is exciting for future nano-medical applications. This paper reports the first synthesis of selenium nanoparticles by femtosecond pulsed laser ablation in de-ionized water. Those pure nanoparticles have been successfully used to inhibit the formation of Candida albicans biofilms. Advanced electron microscopy images showed that selenium nanoparticles easily adhere on the biofilm, then penetrate into the pathogen, and consequently damage the cell structure by substituting with sulfur. 50% inhibition of Candida albicans biofilm was obtained at only 25 ppm. Finally, the two physical parameters proved to affect strongly the viability of Candida albicans are the crystallinity and particle size.

Indexed as

Antifungal AgentsBiofilmsCandida albicansCandidiasisHumansLasersNanoparticlesNanotechnologySeleniumAntifungal AgentsSeleniumFemtosecond laserHospital-acquired infectionsLaser-induced bubblesNosocomial diseasesSize effectStructural phase transition

Identifiers

PMID27793789
PMCPMC5660926
OpenAlexW2535384596

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.