Evidence map›Paper›PMID 27793592›Full record

ArticleVision research2017

Distribution differences of macular cones measured by AOSLO: Variation in slope from fovea to periphery more pronounced than differences in total cones.

Ann E Elsner, Toco Y P Chui, Lei Feng, Hong Xin Song, Joel A Papay, Stephen A Burns

Abstract read
In one paragraph

Article in Vision research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Modeling Human Macular Cone Photoreceptor Spatial Distribution.Investigative ophthalmology & visual science · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Cone Photoreceptors in Diabetic Patients.Frontiers in medicine · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Cones in ageing and harsh environments: the neural economy hypothesis.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2020
    Review
  15. Article
  16. Adaptive optics imaging of the human retina.Progress in retinal and eye research · 2019
    Review
  17. Article
  18. Photoreceptor-Based Biomarkers in AOSLO Retinal Imaging.Investigative ophthalmology & visual science · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ann E ElsnerIndiana University School of Optometry, 800 E. Atwater Ave, Bloomington, IN 47405, United States. Electronic address: aeelsner@indiana.edu.
Toco Y P ChuiIndiana University School of Optometry, 800 E. Atwater Ave, Bloomington, IN 47405, United States. Electronic address: ypchui@indiana.edu.
Lei FengIndiana University School of Optometry, 800 E. Atwater Ave, Bloomington, IN 47405, United States. Electronic address: fengleisx@126.com.
Hong Xin SongIndiana University School of Optometry, 800 E. Atwater Ave, Bloomington, IN 47405, United States. Electronic address: hongxin_song@urmc.rochester.edu.
Joel A PapayIndiana University School of Optometry, 800 E. Atwater Ave, Bloomington, IN 47405, United States. Electronic address: japapay@indiana.edu.
Stephen A BurnsIndiana University School of Optometry, 800 E. Atwater Ave, Bloomington, IN 47405, United States. Electronic address: staburns@indiana.edu.
Indiana University Bloomington · US

Funding

INVESTIGATIONS OF HUMAN CONE PIGMENT KINETICSR01EY004395 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI BURNS, STEPHEN A · 1985 to 2014
$5.7M
SPATIAL EXTENT OF RETINAL DAMAGER01EY007624 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI ELSNER, ANN E · 1995 to 2012
$4.4M
Adaptive Optics Imaging of Human Retinal Vascular Structure and FunctionR01EY024315 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI BURNS, STEPHEN A · 2015 to 2024
$4.3M
Core Support for Vision Research at Indiana UniversityP30EY019008 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI BURNS, STEPHEN A · 2009 to 2013
$2.1M
Lowering the Cost of Imaging for Retinal Microvasculature in Diabetic PatientsR41EY026105 · NEI · AEON IMAGING, LLC · PI ELSNER, ANN E · 2015 to 2015
$222k
NEI NIH HHS P30 EY019008NEI NIH HHS R01 EY004395NEI NIH HHS R01 EY007624NEI NIH HHS R01 EY024315NEI NIH HHS R41 EY026105
6 · The paper itself

Abstract

Large individual differences in cone densities occur even in healthy, young adults with low refractive error. We investigated whether cone density follows a simple model that some individuals have more cones, or whether individuals differ in both number and distribution of cones. We quantified cones in the eyes of 36 healthy young adults with low refractive error using a custom adaptive optics scanning laser ophthalmoscope. The average cone density in the temporal meridian was, for the mean±SD, 43,216±6039, 27,466±3496, 14,996±1563, and 12,207±1278cones/mm

Indexed as

AdolescentAdultCell CountFemaleFovea CentralisHumansMaleOphthalmoscopesOphthalmoscopyRetinaRetinal Cone Photoreceptor CellsVisual AcuityYoung AdultAdaptive optics scanning laser ophthalmoscopyCone densityCone distributionConesFoveaFoveal specialization

Identifiers

PMID27793592
PMCPMC5346455
OpenAlexW2548448184

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.