Evidence map›Paper›PMID 27793158›Full record

ArticleCardiovascular ultrasound2016

Clinical and echocardiographic predictors of mortality in acute pulmonary embolism.

Talal Dahhan, Irfan Siddiqui, Victor F Tapson, Eric J Velazquez, Stephanie Sun, Clemontina A Davenport, Zainab Samad, Sudarshan Rajagopal

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular ultrasound, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Predictors for Prognosis in Patients With Nonfatal Pulmonary Embolism: A Registry-Based Cohort Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018
    Trial
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  5. Use of the PaOJournal of thoracic disease · 2025
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  20. Controlling Nutritional Status Score Predicts In-Hospital Mortality in Acute Pulmonary Embolism.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Talal DahhanDepartment of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Duke University, Durham, NC, USA.
Irfan SiddiquiDepartment of Medicine, East Carolina University, Greenville, NC, USA.
Victor F TapsonDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA.
Eric J VelazquezDepartment of Medicine, Division of Cardiology, Duke University, Durham, NC, USA.
Stephanie SunDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.
Clemontina A DavenportDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.
Zainab SamadDepartment of Medicine, Division of Cardiology, Duke University, Durham, NC, USA.
Sudarshan RajagopalDepartment of Medicine, Division of Cardiology, Duke University, Durham, NC, USA. sudarshan.rajagopal@duke.edu.
Duke University · USCedars-Sinai Medical Center · USDuke Medical Center · USDuke University Hospital · USEast Carolina University · US

Funding

Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
Noncanonical Receptor Signaling in Pulmonary Arterial HypertensionK08HL114643 · NHLBI · DUKE UNIVERSITY · PI RAJAGOPAL, SUDARSHAN K · 2013 to 2017
$607k
NCATS NIH HHS UL1 TR001117NHLBI NIH HHS K08 HL114643
6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the utility of adding quantitative assessments of cardiac function from echocardiography to clinical factors in predicting the outcome of patients with acute pulmonary embolism (PE).

methodsPatients with a diagnosis of acute PE, based on a positive ventilation perfusion scan or computed tomography (CT) chest angiogram, were identified using the Duke University Hospital Database. Of these, 69 had echocardiograms within 24-48 h of the diagnosis that were suitable for offline analysis. Clinical features that were analyzed included age, gender, body mass index, vital signs and comorbidities. Echocardiographic parameters that were analyzed included left ventricular (LV) ejection fraction (EF), regional, free wall and global RV speckle-tracking strain, RV fraction area change (RVFAC), Tricuspid Annular Plane Systolic Excursion (TAPSE), pulmonary artery acceleration time (PAAT) and RV myocardial performance (Tei) index. Univariable and multivariable regression statistical analysis models were used.

resultsOut of 69 patients with acute PE, the median age was 55 and 48 % were female. The median body mass index (BMI) was 27 kg/m

conclusionThe addition of echocardiographic assessment of RV function to clinical parameters improved the prediction of outcomes for patients with acute PE. Larger studies are needed to validate these findings.

Indexed as

Acute DiseaseAdultAgedEchocardiography, DopplerFemaleFollow-Up StudiesHeart VentriclesHumansMaleMiddle AgedPulmonary EmbolismRetrospective StudiesSurvival RateUnited StatesVentricular Dysfunction, RightEchocardiographyPulmonary embolismRight ventricular functionSpeckle-tracking echocardiography

Identifiers

PMID27793158
PMCPMC5086059
OpenAlexW2541741511

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.