Trial reportBMC oral health2016
Consequences of orthodontic treatment in malocclusion patients: clinical and microbial effects in adults and children.
Trial report in BMC oral health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Prevalence of malocclusion in Turkish children and adolescents: A systematic review and meta-analysis.Clinical and experimental dental research · 2023Pooled it
- Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review.Clinical oral investigations · 2022Pooled it
- Skeletal and dentoalveolar effects of class II malocclusion treatment using bi-maxillary skeletal anchorage: a systematic review.BMC oral health · 2022Pooled it
- The microbial changes in subgingival plaques of orthodontic patients: a systematic review and meta-analysis of clinical trials.BMC oral health · 2017Pooled it
- Global distribution of malocclusion traits: A systematic review.Dental press journal of orthodonticsPooled it
- [Comparative study on the clinical performance of concealable traction hook spherical buccal tubes versus conventional rectangular buccal tubes].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Trial
- Salivary pH changes under the effect of stainless steel versus elastomeric ligatures in fixed orthodontic patients: a single-center, randomized controlled clinical trial.BMC oral health · 2021Trial
- Review
- Sex-Dependent Prevalence of Sagittal Skeletal, Dental Malocclusions in Romanian Orthodontic Patients: An Observational Study.Journal of clinical medicine · 2026Article
- Reliability assessment of the non-rigid registration for central incisors movement evaluation based on CBCT registration.Scientific reports · 2026Article
- Malocclusion in 12-13-years old Polish adolescents - an analysis across a spectrum of parental, birth, and developmental factors.BMC oral health · 2025Article
- Low-Friction and Corrosion-Resistant Orthodontic Stainless Steel Archwires with Functional Carbon Films.Nanomaterials (Basel, Switzerland) · 2025Article
- Exploring the Role of Oral Microbiota in the Pathophysiology and Treatment of Bruxism.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Review
- Evaluating the Diagnostic Proficiency Among a Sample of Final Stage Dental Students in Some Orthodontic Cases: A Comprehensive Analysis of Clinical Competence.Dentistry journal · 2025Article
- Automated orthodontic diagnosis via self-supervised learning and multi-attribute classification using lateral cephalograms.Biomedical engineering online · 2025Article
- Impact of parental oral health literacy on orthodontic treatment need in schoolchildren.Dental press journal of orthodontics · 2025Article
- Micro-implant anchorage in adolescent orthodontics: a promising and advantageous option.American journal of translational research · 2025Article
- Article
- Evaluation of Sella Turcica Variations in Lateral Cephalometric Radiographs and its Association with Malocclusion.Acta stomatologica Croatica · 2024Article
- The Influence of Orthodontic Treatment on Periodontal Health between Challenge and Synergy: A Narrative Review.Dentistry journal · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalocclusion is a common disease of oral and maxillofacial region. The study was aimed to investigate levels changes of periodontal pathogens in malocclusion patients before, during and after orthodontic treatments, and to confirm the difference between adults and children.
methodOne hundred and eight malocclusion patients (46 adults and 62 children at the school-age) were randomly selected and received orthodontic treatment with fixed orthodontic appliances. Subgingival plaques were Porphyromonas gingivalis (P.gingivalis), Fusobacterium nucleatum (F. nucleatum), Prevotella intermedia (P. intermedia) and Tannerella forsythensis (T. forsythensis) collected from the observed regions before and after treatment. Clinical indexes, including plaque index (PLI), gingival index (GI), sulcus bleeding index (SBI), probing depth (PD) and attachment loss (AL) of observed teeth were examined.
resultsThe detection rates of P.gingivalis, F. nucleatum, P. intermedia and T. forsythensis increased from baseline to the third month without significant difference, and then returned to pretreatment levels 12 month after applying fixed orthodontic appliances. Adults' percentage contents of P.gingivalis, F. nucleatum, P. intermedia and T. forsythensis were significantly higher than those of children at baseline and the first month, but not obvious at the third month. PLI and SBI were increased from baseline to the first and to the third month both in adults and children groups. Besides, PD were increased from baseline to first month, followed by a downward trend in the third month; however, all patients were failed to detect with AL.
conclusionsPeriodontal and microbiological statuses of malocclusion patients may be influenced by fixed orthodontic appliances in both adults and children, more significant in children than in adults. Some microbiological indexes have synchronous trend with the clinical indexes. Long-term efficacy of fixed orthodontic appliances for malocclusion should be confirmed by future researches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.