ArticleBMC microbiology2016
Inhibition of Staphylococcus aureus biofilm by Lactobacillus isolated from fine cocoa.
Article in BMC microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 103 citations in OpenAlex.
- In Vitro evaluation of cell-free supernatants from soil-derived Bacillus sp. for antibiofilm and antioxidant activities.Molecular biology reports · 2026Article
- Oral administration of Lactiplantibacillus plantarum 6.2 mitigates acute lung injury via immunostaining of the TLR4/NF-κB pathway and reduction of IL-17 in lung tissue.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Antibiofilm activity of Limosilactobacillus fermentum SH2 and Lactococcus lactis extracts against strains of methicillin-resistant Staphylococcus aureus, Staphylococcus hominis SH7, and Pseudomonas aeruginosa.Molecular biology reports · 2026Article
- Synthesis, in-vitro and in-silico bioactivity and computational studies of pyrene and p-methoxycinnamaldehyde linked 4-hydroxycoumarins.Scientific reports · 2026Article
- Antibacterial Potential ofFoods (Basel, Switzerland) · 2026Article
- Association of low progesterone levels and periodontal disease with threatened preterm labor.Scientific reports · 2026Article
- Potential of Fermented Food-DerivedInternational journal of molecular sciences · 2026Article
- Oral supplementation with Lactiplantibacillus plantarum 6.2 in rats enhances bone and epithelial tissue repair by inhibiting NF-κB protein and promoting extracellular matrix synthesis via TGF-β.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
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- Postbiotics from lactic acid bacteria as promising alternatives against urinary tract pathogens.Frontiers in microbiology · 2026Article
- Anti-Biofilm Properties of Cell-Free Supernatant fromMicroorganisms · 2025Article
- Essential oils and Lactobacillus metabolites as alternative antibiofilm agents against foodborne bacteria and molecular analysis of biofilm regulatory genes.Scientific reports · 2025Article
- Characterization and Probiotic Potential ofMicroorganisms · 2025Article
- Immunomodulation in Non-traditional Therapies for Methicillin-resistant Staphylococcus aureus (MRSA) Management.Current microbiology · 2024Review
- Characterization of probiotics isolated from dietary supplements and evaluation of metabiotic-antibiotic combinations as promising therapeutic options against antibiotic-resistant pathogens using time-kill assay.BMC complementary medicine and therapies · 2024Article
- Potential antivirulence and antibiofilm activities of sub-MIC of oxacillin against MDR S. aureus isolates: an in-vitro and in-vivo study.BMC microbiology · 2024Article
- Molecular Aspects of the Functioning of Pathogenic Bacteria Biofilm Based onInternational journal of molecular sciences · 2024Review
- Review
- Anti-adherence Activity of Monomicrobial and Polymicrobial Food-Derived Enterococcus spp. Biofilms Against Pathogenic Bacteria.Current microbiology · 2023Article
- ESKAPEE Pathogen Biofilm Control on Surfaces with ProbioticAntibiotics (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBiofilm production represents an important virulence and pathogenesis factor for Staphylococcus aureus. The formation of biofilms on medical devices is a major concern in hospital environments, as they can become a constant source of infection. Probiotic bacteria, such as Lactobacillus fermentum and L. plantarum, have been found to inhibit biofilm formation; however little is known about the underlying mechanism. In this study, we tested the activity of supernatants produced by L. fermentum TCUESC01 and L. plantarum TCUESC02, isolated during the fermentation of fine cocoa, against S. aureus CCMB262 biofilm production. We measured inhibition of biofilm formation in vitro and analyzed biofilm structure by confocal and electronic microscopy. Additionally, we quantified the expression of S. aureus genes icaA and icaR involved in the synthesis of the biofilm matrix by real-time PCR.
resultsBoth Lactobacillus supernatants inhibited S. aureus growth. However, only L. fermentum TCUESC01 significantly reduced the thickness of the biofilm, from 14 μm to 2.83 μm (at 18 mg∙mL
conclusionsL. fermentum TCUESC01 reduces the formation of S. aureus biofilm under subinhibitory conditions. Inhibition of biofilm production probably depends on modulation of the ica operon.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.