Evidence map›Paper›PMID 27792286›Full record

ArticleJournal of tissue engineering and regenerative medicine2018

An integrated theoretical-experimental approach to accelerate translational tissue engineering.

Rachel H Coy, Owen R Evans, James B Phillips, Rebecca J Shipley

Abstract read
In one paragraph

Article in Journal of tissue engineering and regenerative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. CombiningJournal of the Royal Society, Interface · 2020
    Article
  6. Strategies for Peripheral Nerve Repair.Current tissue microenvironment reports · 2020
    Review
  7. Vascularization Strategies for Peripheral Nerve Tissue Engineering.Anatomical record (Hoboken, N.J. : 2007) · 2018
    Review
  8. Polymeric 3D Printed Structures for Soft-Tissue Engineering.Journal of applied polymer science · 2018
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rachel H CoyCoMPLEX, University College London, London, UK.ORCID 0000-0001-6925-4461
Owen R EvansDepartment of Mathematics, Columbia University, USA.
James B PhillipsBiomaterials and Tissue Engineering, University College London, London, UK.
Rebecca J ShipleyDepartment of Mechanical Engineering, University College London, London, UK.

Funding

British Heart Foundation SP/08/004
6 · The paper itself

Abstract

Implantable devices utilizing bioengineered tissue are increasingly showing promise as viable clinical solutions. The design of bioengineered constructs is currently directed according to the results of experiments that are used to test a wide range of different combinations and spatial arrangements of biomaterials, cells and chemical factors. There is an outstanding need to accelerate the design process and reduce financial costs, whilst minimizing the required number of animal-based experiments. These aims could be achieved through the incorporation of mathematical modelling as a preliminary design tool. Here we focus on tissue-engineered constructs for peripheral nerve repair, which are designed to aid nerve and blood vessel growth and repair after peripheral nerve injury. We offer insight into the role that mathematical modelling can play within tissue engineering, and motivate the use of modelling as a tool capable of improving and accelerating the design of nerve repair constructs in particular. Specific case studies are presented in order to illustrate the potential of mathematical modelling to direct construct design. Copyright © 2016 The Authors Journal of Tissue Engineering and Regenerative Medicine Published by John Wiley & Sons Ltd.

Indexed as

Models, TheoreticalTranslational Research, BiomedicalNerve RegenerationTissue EngineeringTissue Scaffoldsmathematical modellingperipheral nerve repairtranslational research

Identifiers

PMID27792286
PMCPMC5811925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.