Evidence map›Paper›PMID 27791453›Full record

ReviewBioengineered2017

New biotechnological applications for Ashbya gossypii: Challenges and perspectives.

Tatiana Q Aguiar, Rui Silva, Lucília Domingues

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineered, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. New Promoters for Metabolic Engineering ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  5. Review
  6. Sporulation inJournal of fungi (Basel, Switzerland) · 2020
    Review
  7. Production of Vitamin B2 (Riboflavin) by Microorganisms: An Overview.Frontiers in bioengineering and biotechnology · 2020
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tatiana Q Aguiara CEB - Centre of Biological Engineering , University of Minho , Braga , Portugal.ORCID http://orcid.org/0000-0003-4368-7597
Rui Silvaa CEB - Centre of Biological Engineering , University of Minho , Braga , Portugal.ORCID http://orcid.org/0000-0002-5803-0769
Lucília Dominguesa CEB - Centre of Biological Engineering , University of Minho , Braga , Portugal.ORCID http://orcid.org/0000-0003-1089-7627
University of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The filamentous fungus Ashbya gossypii has long been considered a paradigm of the White Biotechnology in what concerns riboflavin production. Its industrial relevance led to the development of a significant molecular and in silico modeling toolbox for its manipulation. This, together with the increasing knowledge of its genome and metabolism has helped designing effective metabolic engineering strategies for optimizing riboflavin production, but also for developing new A. gossypii strains for novel biotechnological applications, such as production of recombinant proteins, single cell oils (SCOs), and flavour compounds. With the recent availability of its genome-scale metabolic model, the exploration of the full biotechnological potential of A. gossypii is now in the spotlight. Here, we will discuss some of the challenges that these emerging A. gossypii applications still need to overcome to become economically attractive and will present future perspectives for these and other possible biotechnological applications for A. gossypii.

Indexed as

AlcoholsAscomycotaBatch Cell Culture TechniquesGenetic EnhancementHydrocarbons, AromaticLipid MetabolismModels, BiologicalNucleosidesProtein EngineeringRecombinant ProteinsRiboflavinAlcoholsHydrocarbons, AromaticNucleosidesRecombinant ProteinsRiboflavinAshbya gossypiibiolipidsflavour compoundsinosinerecombinant proteinssingle cell oilsvitamins

Identifiers

PMID27791453
PMCPMC5553342
OpenAlexW2540375764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.