ArticleProceedings of the National Academy of Sciences of the United States of America2016
Chilling-induced tomato flavor loss is associated with altered volatile synthesis and transient changes in DNA methylation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 112 papers.
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Who cites it
112 citing papers in PubMed, 324 citations in OpenAlex.
- MdWRKY125 bridges cold condition and fruit flavor by activating the sucrose synthase geneaBIOTECH · 2026Article
- Active Packaging, Fruit Volatilome, and the Preservation of Taste and Aroma Quality in Fresh Fruits: A Review.Foods (Basel, Switzerland) · 2026Review
- OfWRKY48 coordinates floral aroma biosynthesis by dual regulation of MEP pathway and carotenoid metabolism inHorticulture research · 2026Article
- Exogenous Melatonin Enhances the Cold Tolerance of Harvested Peach (Plants (Basel, Switzerland) · 2026Article
- New insights into controlling horticultural crop quality deterioration caused by cold stress: epigenetic modification.Horticulture research · 2026Article
- Light regulates tomato fruit metabolome via SlDML2-mediated global DNA demethylation.Journal of integrative plant biology · 2026Article
- Regulation of apocarotenoids for quality improvement and biofortification of horticultural crops.Journal of advanced research · 2026Review
- Exogenous proline regulates the antioxidation system and fruit quality of cherry tomatoes under chilling storage: Integrated physiological, metabolomic, and transcriptomic study.Food chemistry. Molecular sciences · 2025Article
- Loss of function of chromatin remodeler OsCLSY4 leads to RdDM-mediated mis-expression of endosperm-specific genes affecting grain qualities.PLoS genetics · 2025Article
- Tomato and its relatives are breaking the genomics barriers.Journal of experimental botany · 2025Review
- XYLEM NAC DOMAIN 1 (EjXND1) relieves cold-induced lignification by negatively regulating the EjHB1-EjPRX12 module in loquat fruit.Journal of advanced research · 2025Article
- DNA Methylation Profile Changes in CpG Islands of Ethylene-Signaling Genes Regulated by Melatonin Were Involved in Alleviating Chilling Injury of Postharvest Tomato Fruit.International journal of molecular sciences · 2025Article
- The H3K27me3 histone mark correlates with repression of colour and aroma development post-harvest in strawberry fruit.Journal of experimental botany · 2025Article
- Genome-Wide Identification and Analysis of DNA Methyltransferase and Demethylase Gene Families in Sweet Potato and Its Diploid Relative.Plants (Basel, Switzerland) · 2025Article
- The Effect of Varying Durations of Post-Harvest Cryogenic Treatments on the Quality of Cabernet Sauvignon Wines.Foods (Basel, Switzerland) · 2025Article
- UDP-glycosyltransferase PpUGT74F2 is involved in fruit immunity via modulating salicylic acid metabolism.Horticulture research · 2025Article
- Two transcription factors play critical roles in mediating epigenetic regulation of fruit ripening in tomato.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The Good, the Bad, and the Epigenetic: Stress-Induced Metabolite Regulation and Transgenerational Effects.Epigenomes · 2025Review
- Effect of Postharvest Storage Temperature and Duration on Tomato Fruit Quality.Foods (Basel, Switzerland) · 2025Article
- Graph pangenome reveals the regulation of malate content in blood-fleshed peach by NAC transcription factors.Genome biology · 2025Article
52 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Commercial tomatoes are widely perceived by consumers as lacking flavor. A major part of that problem is a postharvest handling system that chills fruit. Low-temperature storage is widely used to slow ripening and reduce decay. However, chilling results in loss of flavor. Flavor-associated volatiles are sensitive to temperatures below 12 °C, and their loss greatly reduces flavor quality. Here, we provide a comprehensive view of the effects of chilling on flavor and volatiles associated with consumer liking. Reduced levels of specific volatiles are associated with significant reductions in transcripts encoding key volatile synthesis enzymes. Although expression of some genes critical to volatile synthesis recovers after a return to 20 °C, some genes do not. RNAs encoding transcription factors essential for ripening, including RIPENING INHIBITOR (RIN), NONRIPENING, and COLORLESS NONRIPENING are reduced in response to chilling and may be responsible for reduced transcript levels in many downstream genes during chilling. Those reductions are accompanied by major changes in the methylation status of promoters, including RIN Methylation changes are transient and may contribute to the fidelity of gene expression required to provide maximal beneficial environmental response with minimal tangential influence on broader fruit developmental biology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.