ArticleProceedings of the National Academy of Sciences of the United States of America2016
Increasing seed size and quality by manipulating BIG SEEDS1 in legume species.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.
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Who cites it
88 citing papers in PubMed, 171 citations in OpenAlex.
- Fine mapping and functional analysis of the candidate gene OFP17, regulating both seed and fruit sizes in cotton.The plant genome · 2026Article
- Challenges and Opportunities with CRISPR-Based Genome Editing in Legume Crops.Functional & integrative genomics · 2026Review
- Article
- Natural variation of theFrontiers in plant science · 2026Article
- Identification of candidate loci regulating seed-associated traits in soybean using genome-wide association study and image-based high-throughput phenotyping.Frontiers in plant science · 2026Article
- Identification of Novel Genetic Loci Related to 100-Seed Weight in the Korean Soybean Core Collection Using a Genome-Wide Association Study.International journal of molecular sciences · 2025Article
- Transcriptome-Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The miR172a-ERF416/413 module regulates soybean seed traits.Journal of integrative plant biology · 2025Article
- Marker Metabolite-Based Multi-Omics Analysis Identifies New Loci Controlling Thousand Seed Weight in Brassica Napus.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- An Australian chickpea pan-genome provides insights into genome organization and offers opportunities for enhancing drought adaptation for crop improvement.Plant biotechnology journal · 2025Article
- Genetic control of stem elongation in common bean and the influence of age and flowering time.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Recent advances in improving yield and immunity through transcription factor engineering.Journal of integrative plant biology · 2025Review
- Conditional QTL/QTN mapping for seed width and mining candidate genes based on soybean FW-RIL population.Molecular genetics and genomics : MGG · 2025Article
- Heterotrimeric G-protein subunits regulate plant architecture, pod development, seed size, and symbiotic nodulation inaBIOTECH · 2025Article
- Loss of phytochromobilin synthase activity leads to larger seeds with higher protein content in soybean.BMC plant biology · 2025Article
- A R2R3-MYB Transcription Factor ofInternational journal of molecular sciences · 2025Article
- Seed-specific expression of phosphatidate phosphohydrolases increases soybean oil content and seed weight.Biotechnology for biofuels and bioproducts · 2025Article
- Identification of superior haplotypes and candidate gene for seed size-related traits in soybean (Molecular breeding : new strategies in plant improvement · 2025Article
- Genome-Wide Identification, Expression and Interaction Analysis ofCurrent issues in molecular biology · 2024Article
- Natural variation in GmSW17 controls seed size in soybean.Nature communications · 2024Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant organs, such as seeds, are primary sources of food for both humans and animals. Seed size is one of the major agronomic traits that have been selected in crop plants during their domestication. Legume seeds are a major source of dietary proteins and oils. Here, we report a conserved role for the BIG SEEDS1 (BS1) gene in the control of seed size and weight in the model legume Medicago truncatula and the grain legume soybean (Glycine max). BS1 encodes a plant-specific transcription regulator and plays a key role in the control of the size of plant organs, including seeds, seed pods, and leaves, through a regulatory module that targets primary cell proliferation. Importantly, down-regulation of BS1 orthologs in soybean by an artificial microRNA significantly increased soybean seed size, weight, and amino acid content. Our results provide a strategy for the increase in yield and seed quality in legumes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.