Evidence map›Paper›PMID 27791114›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2016

Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain.

Sayan Nandi, Dhruva Chandramohan, Luana Fioriti, Ari M Melnick, Jean M Hébert, Christopher E Mason, Priyamvada Rajasethupathy, Eric R Kandel

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 2 pooled it
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
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  16. Insights in piRNA targeting rules.Wiley interdisciplinary reviews. RNA · 2023
    Article
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  18. Article
  19. Review
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Sayan NandiDepartment of Neuroscience, Columbia University, New York, NY 10032.
Dhruva ChandramohanDepartment of Physiology, Weill Cornell Medical College, New York, NY 10065.
Luana FioritiDepartment of Neuroscience, Columbia University, New York, NY 10032.
Ari M MelnickDepartment of Medicine, Weill Cornell Medical College, New York, NY 10065.
Jean M HébertDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461.
Christopher E MasonDepartment of Physiology, Weill Cornell Medical College, New York, NY 10065.
Priyamvada RajasethupathyDepartment of Bioengineering, Stanford University, Stanford, CA 94305; priya@rockefeller.edu erk5@columbia.edu.
Eric R KandelDepartment of Neuroscience, Columbia University, New York, NY 10032; priya@rockefeller.edu erk5@columbia.edu.
Cornell University · USColumbia University · USAlbert Einstein College of Medicine · USHoward Hughes Medical Institute · USStanford University · US

Funding

Epigenome Interactions in Complex Neurogenetic DisordersR01NS076465 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI MASON, CHRISTOPHER EDWARD, ROSS, MARGARET ELIZABETH · 2011 to 2015
$5.8M
Genetic Analysis of Forebrain Patterning & NeurogenesisR01MH070596 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI HEBERT, JEAN M · 2006 to 2017
$3.9M
Tri-Institutional Training Program in Computational Biology & MedicineT32GM083937 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHRISTINI, DAVID J. · 2009 to 2018
$3.1M
Molecular Targeting of Diffuse Large B-cell LymphomaR01CA143032 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MELNICK, ARI M. · 2010 to 2014
$2.8M
Transcriptional silencing by the BCL6 oncoproteinR01CA104348 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MELNICK, ARI M. · 2004 to 2014
$2.6M
Targeting the heat shock response for the therapy of DLBCLR01CA155226 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHIOSIS, GABRIELA, MELNICK, ARI M. · 2011 to 2015
$2.5M
WNTs, FGFs, and BMPs Induce and Maintain the TelencephalonR01MH083804 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI HEBERT, JEAN M · 2009 to 2013
$2.0M
Trancriptional silencing by the Bcl-6 OncoproteinR56CA104348 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MELNICK, ARI M. · 2009 to 2009
$267k
NCI NIH HHS R01 CA104348NCI NIH HHS R01 CA143032NCI NIH HHS R01 CA155226NCI NIH HHS R56 CA104348NIGMS NIH HHS T32 GM083937NIMH NIH HHS R01 MH070596NIMH NIH HHS R01 MH083804NINDS NIH HHS R01 NS076465
6 · The paper itself

Abstract

Piwi-interacting RNAs (piRNAs), long thought to be restricted to germline, have recently been discovered in neurons of

Indexed as

behaviorDNA methylationendogenous siRNApiwi-interacting RNAtransposon

Identifiers

PMID27791114
PMCPMC5111663
OpenAlexW2535271053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.