Evidence map›Paper›PMID 27791086›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2016

Chromosome-refolding model of mating-type switching in yeast.

Barış Avşaroğlu, Gabriel Bronk, Kevin Li, James E Haber, Jane Kondev

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Yeast ATM and ATR kinases use different mechanisms to spread histone H2A phosphorylation around a DNA double-strand break.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  7. Frequency of DNA end joiningProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Barış AvşaroğluDepartment of Physics, Brandeis University, Waltham, MA 02454.
Gabriel BronkDepartment of Physics, Brandeis University, Waltham, MA 02454.
Kevin LiDepartment of Physics, Brandeis University, Waltham, MA 02454.
James E HaberDepartment of Biology, Brandeis University, Waltham, MA 02454; haber@brandeis.edu kondev@brandeis.edu.
Jane KondevDepartment of Physics, Brandeis University, Waltham, MA 02454; haber@brandeis.edu kondev@brandeis.edu.
Brandeis University · US

Funding

Recombination Mechanisms in Yeast Cell DifferentiationR37GM020056 · NIGMS · BRANDEIS UNIVERSITY · PI HABER, JAMES E · 2007 to 2016
$5.5M
RECOMBINATION MECHANISMS IN YEAST CELL DIFFERENTIATIONR01GM020056 · NIGMS · BRANDEIS UNIVERSITY · PI HABER, JAMES E · 1985 to 2006
$3.4M
Quantitative Biology: a Graduate Curriculum Linking the Physical and Biomedical ST32EB009419 · NIBIB · BRANDEIS UNIVERSITY · PI GELLES, JEFF, KONDEV, JANE · 2009 to 2018
$2.8M
NIBIB NIH HHS T32 EB009419NIGMS NIH HHS R01 GM020056NIGMS NIH HHS R37 GM020056
6 · The paper itself

Abstract

Chromosomes are folded into cells in a nonrandom fashion, with particular genetic loci occupying distinct spatial regions. This observation raises the question of whether the spatial organization of a chromosome governs its functions, such as recombination or transcription. We consider this general question in the specific context of mating-type switching in budding yeast, which is a model system for homologous recombination. Mating-type switching is induced by a DNA double-strand break (DSB) at the

Indexed as

chromosome organizationhomologous recombinationquantitative fluorescent microscopyrandom-walk polymersstatistical physics

Identifiers

PMID27791086
PMCPMC5111656
OpenAlexW2536568252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.