Evidence map›Paper›PMID 27790758›Full record

ArticleAddiction (Abingdon, England)2017

Concurrent polysubstance use in a longitudinal study of US youth: associations with sexual orientation.

Aleksandar Kecojevic, Hee-Jin Jun, Sari L Reisner, Heather L Corliss

Open access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. The Association of Stigma, School, and Family Factors with Patterns of Substance Use Among LGBTQ Youth.Prevention science : the official journal of the Society for Prevention Research · 2024
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  16. Same-day use of cigarettes, alcohol, and cannabis among sexual minority and heterosexual young adult smokers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Aleksandar KecojevicDepartment of Public Health, William Paterson University New Jersey, Wayne, NJ, USA.
Hee-Jin JunGraduate School of Public Health, Division of Health Promotion and Behavioral Science, San Diego State University, San Diego, CA, USA.
Sari L ReisnerDivision of General Pediatrics, Boston Children's Hospital/Harvard Medical School, Boston, MA, USA.
Heather L CorlissGraduate School of Public Health, Division of Health Promotion and Behavioral Science, San Diego State University, San Diego, CA, USA.
Brigham and Women's Hospital · USHarvard University · USSan Diego State University · USWilliam Paterson University · US

Funding

Substance Disorders, Substance Use Treatment, and Sexual Orientation in YouthR01DA033974 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CORLISS, HEATHER L · 2013 to 2017
$3.5M
Sexual Orientation and Health Disparities in AdolescenceR01HD045763 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI AUSTIN, S BRYN · 2004 to 2007
$812k
Adolescent Substance Use and the Transition to Adulthood in Sexual Minority YouthK01DA023610 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI CORLISS, HEATHER L · 2007 to 2011
$689k
DIET, ACTIVITY, AND ADOLESCENT WEIGHT CHANGESR01DK046834 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI COLDITZ, GRAHAM A · 1996 to 1999
–
NICHD NIH HHS R01 HD045763NIDA NIH HHS K01 DA023610NIDA NIH HHS R01 DA033974NIDDK NIH HHS R01 DK046834
6 · The paper itself

Abstract

aimsTo estimate longitudinal associations between self-reported sexual orientation and past-year polysubstance use among youth, and test how gender, age and early onset of tobacco and alcohol use contributed to variation in polysubstance use.

designLongitudinal community-based cohort of US adolescents from the Growing Up Today Study (GUTS 1) (n = 16 873) followed from ages 12-29 years.

settingUnited States of America.

participantsA total of 13 519 individuals (7839 females; 5680 males) who responded to at least one of five self-administered questionnaires from 1999 to 2010. Ninety-three per cent reported their race/ethnicity as non-Hispanic white. MEASUREMENTS: Multivariable repeated measures generalized estimating equations estimated relative risks (RRs) of concurrent polysubstance use (i.e. past 12-month use of three or more substances) comparing sexual orientation minority youth [i.e. mostly heterosexual (MH), bisexual (BI), gay/lesbian (GL)] to their same-gender, completely heterosexual (CH) counterparts. Mediation analyses tested whether early onset of tobacco and/or alcohol use explained relationships between sexual orientation and concurrent polysubstance use.

findingsCompared with their same-gender CH peers, sexual minorities evidenced higher risk for concurrent polysubstance use over all repeated measures [risk ratios (RRs) for sexual minority subgroups: from 1.63-2.91, P-values: <0.001] and for all age groups (RRs: from 1.50-4.04, P-values: < 0.05-< 0.001), except GL males aged 18-20 years. Differences between sexual minorities and CHs were larger among females than males (P-values for sexual orientation × gender interactions were < 0.05 for MHs and BIs), and among younger versus older ages (P-values for sexual orientation × age interactions were < 0.05, except for BI males). Sexual minorities' younger age of smoking and/or drinking initiation contributed to their elevated polysubstance use (% of effect explained was between 9.4-24.3, P-values: 0.04-< 0.001), except among GL males.

conclusionsSexual minority youth in the United States, and in particular younger females, appear to be at disproportionate risk for concurrent past-year polysubstance use. Early onset of smoking and drinking may contribute to elevated risk of polysubstance use among sexual minorities.

Indexed as

AdolescentAdultAge FactorsAlcohol DrinkingBisexualityCase-Control StudiesChildFemaleHeterosexualityHomosexualityHumansLongitudinal StudiesMaleOdds RatioSex FactorsSexual and Gender MinoritiesAdolescentsearly onset of substance useemerging adultslongitudinal studypolysubstance usesexual orientation

Identifiers

PMID27790758
PMCPMC5339035
OpenAlexW2544841744

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.