Evidence map›Paper›PMID 27790644›Full record

ArticleBiochemistry & molecular biology journal2016

Hemozoin Regulates iNOS Expression by Modulating the Transcription Factor NF-κB in Macrophages.

Ravi Ranjan, Manjula Karpurapu, Asha Rani, Athar H Chishti, John W Christman

Open access · hybridAbstract read
In one paragraph

Article in Biochemistry & molecular biology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ravi RanjanDepartment of Medicine, University of Illinois, Chicago, Illinois, USA.
Manjula KarpurapuDepartment of Internal Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, The Ohio State University, Columbus, Ohio, USA.
Asha RaniDepartment of Medicine, University of Illinois, Chicago, Illinois, USA.
Athar H ChishtiDepartment of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, USA.
John W ChristmanDepartment of Internal Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, The Ohio State University, Columbus, Ohio, USA.
The Ohio State University · USUniversity of Illinois Chicago · US

Funding

Role of erythrocyte band 3 in malaria adhesionR01HL060961 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHISHTI, ATHAR H. · 1998 to 2023
$5.9M
Macrophage Gene Expression in Acute Lung InflammationR01HL075557 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHRISTMAN, JOHN W · 2004 to 2016
$4.8M
NHLBI NIH HHS R01 HL060961NHLBI NIH HHS R01 HL075557
6 · The paper itself

Abstract

Hemozoin (Hz) is released from ruptured erythrocytes during malaria infection caused by

Indexed as

HemozoinInducible nitric oxide synthaseLipopolysaccharideMacrophageMalariaSepsis

Identifiers

PMID27790644
PMCPMC5079181
OpenAlexW2520661039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.