Evidence map›Paper›PMID 27790596›Full record

ReviewJournal of clinical and diagnostic research : JCDR2016

Epithelial - Mesenchymal Interactions in Tooth Development and the Significant Role of Growth Factors and Genes with Emphasis on Mesenchyme - A Review.

Jaya Sekharan Vannadil Puthiyaveetil, Kasim Kota, Roopesh Chakkarayan, Jithesh Chakkarayan, Abdul Kabeer Padinhare Thodiyil

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Proteomic analysis of dental pulp from deciduous teeth in comparison to permanent teeth: an in-vitro study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Correlation of Immunohistochemical Biomarkers and Differential Staining Techniques to Investigate the Role of Subepithelial Hyalinization in the Aggressiveness of Odontogenic Keratocyst.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. [Association between root abnormalities and related pathogenic genes in patients with generalized aggressive periodontitis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jaya Sekharan Vannadil PuthiyaveetilSenior Lecturer, Department of Oral Pathology and Microbiology, Kannur Dental College , Kannur, Kerala, India .
Kasim KotaProfessor and Head, Department of Oral Pathology and Microbiology, Kannur Dental College , Kannur, Kerala, India .
Roopesh ChakkarayanSenior Lecturer, Department of Conservative Dentistry and Endodontics, Kannur Dental College , Kannur, Kerala, India .
Jithesh ChakkarayanReader, Department of Orthodontics and Dentofacial Orthopaedics, Kannur Dental College , Kannur, Kerala, India .
Abdul Kabeer Padinhare ThodiyilPostgraduate Trainee, Department of Oral Pathology and Microbiology, Kannur Dental College , Kannur, Kerala, India .
Kannur Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent advancements in medical research field mainly highlights the genetic and molecular aspects of various disease processes and related treatment options, in a specialized "custom-made" approach. The medical and dental field has made tremendous progress in providing even with the smallest insight into pathological entities, thus, making patient management more fruitful. But, short comings have occurred in dental treatments involving odontogenic lesions mainly due to poor understanding of the developmental cycle involved during early stages of developmental process. Multiple numbers of interactions take place during embryo formation and further proliferation of tissue. One such important step is the interaction between epithelium and mesenchyme which tantamount to functional requirements of an individual tooth. The role of extra cellular molecules and genes has to be studied in depth to assess the impact and significance attached to it as the synergistic function of various elements underlines the complex process of development.

Indexed as

MetalloproteasesNeuroectodermal odontogenesisOrganogenesisPrimordia

Identifiers

PMID27790596
PMCPMC5072096
OpenAlexW2529902757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.