ArticleJournal of clinical and diagnostic research : JCDR2016
Hemostasis and Post-operative Care of Oral Surgical Wounds by Hemcon Dental Dressing in Patients on Oral Anticoagulant Therapy: A Split Mouth Randomized Controlled Clinical Trial.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The effectiveness of chitosan as a hemostatic in dentistry in patients with antiplatelet/anticoagulant therapy: systematic review with meta-analysis.BMC oral health · 2024Pooled it
- Perioperative Management of Antithrombotic Therapy in Patients Who Undergo Dental Procedures: A Systematic Review of the Literature and Network Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Comparative Evaluation of Local Hemostatic Agents in Minor Oral Surgical Procedures: A Randomized Clinical Trial.Cureus · 2025Article
- Biomaterial-Based and Surgical Approaches to Local Hemostasis in Contemporary Oral Surgery: A Narrative Review.Journal of functional biomaterials · 2025Review
- Tea Bags for Controlling Postoperative Bleeding after Extraction of Teeth: A Review of Literature.Journal of pharmacy & bioallied sciences · 2025Review
- Is chitosan-based dressing more effective than gauze pressure in achieving early hemostasis after dental extractions in patients with deranged coagulation profiles?Archives of craniofacial surgery · 2025Article
- Applications of chitosan in oral health and diseases.Frontiers in oral health · 2025Review
- Management of Patients Receiving Anticoagulation Therapy in Dental Practice: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- A "Tie-Over" Hemostatic Approach in Emergency Department: An Alternative Option for Recurrent Episodes of Postoperative Intraoral Hemorrhage.Journal of maxillofacial and oral surgery · 2024Article
- The effect of different hemostatic agents following dental extraction in patients under oral antithrombotic therapy: a network meta-analysis.Scientific reports · 2023Article
- Experts' consensus on perioperative management of tooth extractions in patients receiving oral antithrombotic treatment.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022Article
- Bleeding disorders in implant dentistry: a narrative review and a treatment guide.International journal of implant dentistry · 2022Review
- Design and Preclinical Evaluation of Chitosan/Kaolin Nanocomposites with Enhanced Hemostatic Efficiency.Marine drugs · 2021Article
- Review
- Effectiveness of local hemostatic measures after tooth extraction in patients on antithrombotic therapy.Clinical oral investigations · 2020Article
- Anticoagulation Use prior to Common Dental Procedures: A Systematic Review.Cardiology research and practice · 2019Review
- Early Wound Healing Score: a system to evaluate the early healing of periodontal soft tissue wounds.Journal of periodontal & implant science · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHemostasis is a fundamental management issue post-operatively in minor oral surgical procedures. To ensure safety and therapeutic efficacy in patients, under oral anti coagulant therapy, is complicated by necessity for frequent determination of prothrombin time or international normalised ratio.
aimThe aim of the study was to determine whether early hemostasis achieved by using Hemcon Dental Dressing (HDD) will affect post-operative care and surgical healing outcome in minor oral surgical procedures. MATERIALS AND
methodsA total of 30 patients, aged 18 years to 90 years, except those allergic to seafood, who consented to participate, were enrolled into this study. Patients were required to have two or more surgical sites so that they would have both surgical and control sites. All patients taking Oral Anticoagulation Therapy (OAT) were included for treatment in the study without altering the anticoagulant regimens. Institutional Review Board approval was obtained for the same. The collected data was subjected to statistical analysis using unpaired t-test.
resultsAll HDD surgically treated sites achieved hemostasis in 1.49 minutes and control wounds in 4.06 minutes (p < 0.001). Post-operative pain at HDD treated sites (1.87,1.27 on 1
conclusionThe HDD has been proven to be a clinically effective hemostatic dressing material that significantly shortens bleeding time following minor oral surgical procedures under local anaesthesia, including those patients taking OAT. Patients receiving the HDD had improved surgical wound healing as compared to controls.
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Registered trials
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