ReviewTuberculosis and respiratory diseases2016
Clinical Practice Guideline of Acute Respiratory Distress Syndrome.
Review in Tuberculosis and respiratory diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- An appraisal of the methodology and quality of evidence of systematic reviews on the efficacy of prone positional ventilation in adult patients with acute respiratory distress syndrome: an umbrella review.Internal and emergency medicine · 2023Pooled it
- Neuromuscular blocking agents for acute respiratory distress syndrome: an updated meta-analysis of randomized controlled trials.Respiratory research · 2020Pooled it
- Ulinastatin treatment for acute respiratory distress syndrome in China: a meta-analysis of randomized controlled trials.BMC pulmonary medicine · 2019Pooled it
- Corticosteroid use and intensive care unit-acquired weakness: a systematic review and meta-analysis.Critical care (London, England) · 2018Pooled it
- Enhancing Cricothyroidotomy Training for Novices Using Three-Dimensional-Printed Patient-Specific Models of a Patient with Obesity.Journal of medical systems · 2025Trial
- Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trial.European journal of medical research · 2024Trial
- Effect of intensivist involvement on clinical outcomes in patients with advanced lung cancer admitted to the intensive care unit.PloS one · 2019Trial
- Methods to monitor and evaluate neuromuscular blockade use in intensive care unit patients with hypoxemic respiratory failure and acute respiratory distress syndrome: a scoping review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Review
- Optimizing Extracorporeal Membrane Oxygenation Gas Exchange: Key Insights for Clinical Management.Tuberculosis and respiratory diseases · 2025Article
- Current corticosteroid therapeutic strategy for community-acquired pneumonia in adults: indications, dosage, and timing.Journal of intensive care · 2025Review
- Association between mechanical power and intensive care unit mortality in Korean patients under pressure-controlled ventilation.Acute and critical care · 2024Article
- Reactive Oxygen Species and Strategies for Antioxidant Intervention in Acute Respiratory Distress Syndrome.Antioxidants (Basel, Switzerland) · 2023Review
- Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases.Experimental and therapeutic medicine · 2023Article
- Guideline-based management of acute respiratory failure and acute respiratory distress syndrome.Journal of intensive care · 2023Review
- Protective effects of pentoxifylline against chlorine-induced acute lung injury in rats.BMC pharmacology & toxicology · 2023Article
- Analgosedation in Critically Ill Adults Receiving Extracorporeal Membrane Oxygenation Support.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2022Review
- Evidence-Based Considerations for the Design of an Open-Source Ventilator: A Systematic Review.Critical care explorations · 2022Review
- Article
- The Physiological Basis of High-Frequency Oscillatory Ventilation and Current Evidence in Adults and Children: A Narrative Review.Frontiers in physiology · 2022Review
- Electrodiagnostic findings in patients with non-COVID-19- and COVID-19-related acute respiratory distress syndrome.Acta neurologica Scandinavica · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is no well-stated practical guideline for mechanically ventilated patients with or without acute respiratory distress syndrome (ARDS). We generate strong (1) and weak (2) grade of recommendations based on high (A), moderate (B) and low (C) grade in the quality of evidence. In patients with ARDS, we recommend low tidal volume ventilation (1A) and prone position if it is not contraindicated (1B) to reduce their mortality. However, we did not support high-frequency oscillatory ventilation (1B) and inhaled nitric oxide (1A) as a standard treatment. We also suggest high positive end-expiratory pressure (2B), extracorporeal membrane oxygenation as a rescue therapy (2C), and neuromuscular blockage for 48 hours after starting mechanical ventilation (2B). The application of recruitment maneuver may reduce mortality (2B), however, the use of systemic steroids cannot reduce mortality (2B). In mechanically ventilated patients, we recommend light sedation (1B) and low tidal volume even without ARDS (1B) and suggest lung protective ventilation strategy during the operation to lower the incidence of lung complications including ARDS (2B). Early tracheostomy in mechanically ventilated patients can be performed only in limited patients (2A). In conclusion, of 12 recommendations, nine were in the management of ARDS, and three for mechanically ventilated patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.