Evidence map›Paper›PMID 27790096›Full record

ArticleFrontiers in neuroanatomy2016

Intranasal Location and Immunohistochemical Characterization of the Equine Olfactory Epithelium.

Alexandra Kupke, Sabine Wenisch, Klaus Failing, Christiane Herden

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexandra KupkeInstitute of Veterinary Pathology, Faculty of Veterinary Medicine, Justus Liebig University GiessenGiessen, Germany; Institute of Virology, Philipps University MarburgMarburg, Germany.
Sabine WenischSmall Animal Clinic c/o Institute of Veterinary Anatomy, Histology and Embryology, Department of Veterinary Clinical Sciences, Justus Liebig University Giessen Giessen, Germany.
Klaus FailingUnit for Biomathematics and Data Processing, Faculty of Veterinary Medicine, Justus Liebig University Giessen Giessen, Germany.
Christiane HerdenInstitute of Veterinary Pathology, Faculty of Veterinary Medicine, Justus Liebig University Giessen Giessen, Germany.
University of Giessen · DEPhilipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The olfactory epithelium (OE) is the only body site where neurons contact directly the environment and are therefore exposed to a broad variation of substances and insults. It can serve as portal of entry for neurotropic viruses which spread via the olfactory pathway to the central nervous system. For horses, it has been proposed and concluded mainly from rodent studies that different viruses, e.g., Borna disease virus, equine herpesvirus 1 (EHV-1), hendra virus, influenza virus, rabies virus, vesicular stomatitis virus can use this route. However, little is yet known about cytoarchitecture, protein expression and the intranasal location of the equine OE. Revealing differences in cytoarchitecture or protein expression pattern in comparison to rodents, canines, or humans might help to explain varying susceptibility to certain intranasal virus infections. On the other hand, disclosing similarities especially between rodents and other species, e.g., horses would help to underscore transferability of rodent models. Analysis of the complete noses of five adult horses revealed that in the equine OE two epithelial subtypes with distinct marker expression exist, designated as

Indexed as

horseimmunohistochemistryolfactory epitheliumstatistical analysissubtypes

Identifiers

PMID27790096
PMCPMC5061740
OpenAlexW2529976020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.