Evidence map›Paper›PMID 27790071›Full record

ArticleEuropean journal of organic chemistry2016

Macrosteres: The Deltic Guanidinium Ion.

Kenji Mishiro, Fanghao Hu, Daniel W Paley, Wei Min, Tristan H Lambert

Abstract read
In one paragraph

Article in European journal of organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Crystal structure ofActa crystallographica. Section E, Crystallographic communications · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kenji MishiroDepartment of Chemistry, Columbia University, 3000 Broadway, New York, NY 10027 USA, , http://www.columbia.edu/cu/chemistry/groups/lambert/.
Fanghao HuDepartment of Chemistry, Columbia University, 3000 Broadway, New York, NY 10027 USA, , http://www.columbia.edu/cu/chemistry/groups/lambert/.
Daniel W PaleyDepartment of Chemistry, Columbia University, 3000 Broadway, New York, NY 10027 USA, , http://www.columbia.edu/cu/chemistry/groups/lambert/.
Wei MinDepartment of Chemistry, Columbia University, 3000 Broadway, New York, NY 10027 USA, , http://www.columbia.edu/cu/chemistry/groups/lambert/.
Tristan H LambertDepartment of Chemistry, Columbia University, 3000 Broadway, New York, NY 10027 USA, , http://www.columbia.edu/cu/chemistry/groups/lambert/.
Columbia University · US

Funding

Enantioselective Catalysis with CyclopropeniminesR01GM102611 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI LAMBERT, TRISTAN H · 2013 to 2017
$1.6M
Optical imaging of small bio-molecules in living cells and tissues by nonlinear Raman microscopy coupled with vibrational tagsR01EB020892 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI MIN, WEI · 2015 to 2018
$1.3M
NIBIB NIH HHS R01 EB020892NIGMS NIH HHS R01 GM102611
6 · The paper itself

Abstract

The "deltic guanidinium" ion is described here as a "macrostere" of the guanidinium ion. The use of the 2,4-dimethoxybenzyl protecting group allows for the synthesis of the fully unsubstituted parent compound and a variety of derivatives bearing multiple N-H functions for the first time. Deltic urea, deltic thiourea, and deltic benzamidine are also synthesized. A comparison of the physical properties of guanidinium and deltic guanidinium ions is provided. The use of a deltic guanidinium dendrimer for cell transport is demonstrated.

Indexed as

cyclopropeniumguanidiniumisostere

Identifiers

PMID27790071
PMCPMC5079176
OpenAlexW2297357053

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.