ReviewOpen access rheumatology : research and reviews2013
The pain-relieving qualities of exercise in knee osteoarthritis.
Review in Open access rheumatology : research and reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Comparative effectiveness of traditional Chinese exercises for knee osteoarthritis: a systematic review and Bayesian network meta-analysis.Frontiers in public health · 2025Pooled it
- Effect of Knee Angle Specific (60°-90°) Combine versus Isolated Kinetic Chain on Post ACL Recovery Outcomes: A Randomized Control Trial.Journal of multidisciplinary healthcare · 2025Trial
- Persons with high Hemophilia Joint Health Scores have reduced functional range of motion during simulated sports activities.Research and practice in thrombosis and haemostasis · 2026Article
- Knee Osteoarthritis: Current Insights Into Pathophysiology and Non-surgical Management Options.Cureus · 2025Review
- Clinical effect and mechanism of aerobic exercise for knee osteoarthritis: a mini review.Frontiers in physiology · 2025Review
- Impact of combined balance and strength exercise program on lower limb energy flow in individuals with knee osteoarthritis.Frontiers in sports and active living · 2025Article
- Article
- Exercise Therapy for Chronic Neck Pain: Tailoring Person-Centred Approaches within Contemporary Management.Journal of clinical medicine · 2023Review
- Article
- EEG theta and beta bands as brain oscillations for different knee osteoarthritis phenotypes according to disease severity.Scientific reports · 2022Observational
- Nonoperative Care Including Rehabilitation Should Be Considered and Clearly Defined Prior to Elective Orthopaedic Surgery to Maximize Optimal Outcomes.Arthroscopy, sports medicine, and rehabilitation · 2022Article
- Patients want their doctors' help to increase physical activity: a cross sectional study in general practice.Scandinavian journal of primary health care · 2021Article
- Cross-sectional analysis of self-reported sedentary behaviors and chronic knee pain among South Korean adults over 50 years of age in KNHANES 2013-2015.BMC public health · 2019Article
- Can pain influence the proprioception and the motor behavior in subjects with mild and moderate knee osteoarthritis?BMC musculoskeletal disorders · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this review article is to explore the role of therapeutic exercise in managing the pain associated with knee osteoarthritis (OA). Therapeutic exercise is often recommended as a first-line conservative treatment for knee OA, and current evidence supports exercise as an effective pain-relieving intervention. We explore the current state of evidence for exercise as a pain-relieving intervention for knee OA. Next, the mechanisms by which knee OA pain occurs and the potential ways in which exercise may act on those mechanisms are discussed. Clinical applicability and future research directions are suggested. Although evidence demonstrates that exercise reduces knee OA pain, optimal exercise mode and dosage have not been determined. In addition, it is not clearly understood whether exercise provides pain relief via peripheral or central mechanisms or a combination of both. Published clinical trials have explored a variety of interventions, but these interventions have not been specifically designed to target pain pathways. Current evidence strongly supports exercise as a pain-relieving option for those with knee OA. Future research needs to illuminate the mechanisms by which exercise reduces the pain associated with knee OA and the development of therapeutic exercise interventions to specifically target these mechanisms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.