ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2017
Association of body weight changes with mortality in incident hemodialysis patients.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of physical frailty and impact on survival in patients with chronic kidney disease: a systematic review and meta-analysis.BMC nephrology · 2023Pooled it
- BMI Category and Survival in Incident Hemodialysis Patients: The Overweight Advantage in an Eastern European Cohort.Journal of clinical medicine · 2026Article
- Impact of Annual Dry Weight Changes on Mortality and Cardiovascular Outcomes in Patients Undergoing Haemodialysis.Journal of cachexia, sarcopenia and muscle · 2025Article
- Safety and efficacy of very low calorie diet in patients receiving haemodialysis therapy.Clinical kidney journal · 2024Article
- Treatment of Type 2 Diabetes Mellitus in Advanced Chronic Kidney Disease for the Primary Care Physician.Cureus · 2024Review
- Poor Nutritional Status Is Associated with Death in a Population of Dialyzed Older Persons.The Journal of frailty & aging · 2024Article
- Obesity Weight Loss Phenotypes in CKD: Findings From the Chronic Renal Insufficiency Cohort Study.Kidney international reports · 2023Article
- Adipose and serum zinc alpha-2-glycoprotein (ZAG) expressions predict longitudinal change of adiposity, wasting and predict survival in dialysis patients.Scientific reports · 2022Article
- Visceral adiposity indicators and cardiovascular risk in hemodialytic patients.Archives of endocrinology and metabolism · 2021Article
- Assessment of cerebral oxygenation response to hemodialysis using near-infrared spectroscopy (NIRS): Challenges and solutions.Journal of innovative optical health sciences · 2021Article
- Pre-kidney transplant unintentional weight loss leads to worse post-kidney transplant outcomes.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Article
- Obesity and bariatric surgery in kidney transplantation: A clinical review.World journal of diabetes · 2021Review
- The effect of protein-enriched snacks on serum albumin concentration in non-selected haemodialysis patients.Journal of nephrology · 2021Observational
- Review
- Changes in metabolic syndrome status affect the incidence of end-stage renal disease in the general population: a nationwide cohort study.Scientific reports · 2021Article
- Approaches to Obesity Management in Dialysis Settings: Renal Dietitian Perspectives.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2020Article
- Cardiac MRI measurements of pericardial adipose tissue volumes in patients on in-centre nocturnal hemodialysis.Journal of nephrology · 2020Article
- Impact of old age on the association between in-center extended-hours hemodialysis and mortality in patients on incident hemodialysis.PloS one · 2020Article
- The obesity paradox: A further consideration in dialysis patients.Seminars in dialysis · 2019Article
- Association between BMI changes and mortality risk in children with end-stage renal disease.Pediatric nephrology (Berlin, Germany) · 2019Article
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12 authors.
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Abstract
backgroundIncident hemodialysis patients may experience rapid weight loss in the first few months of starting dialysis. However, trends in weight changes over time and their associations with survival have not yet been characterized in this population.
methodsIn a large contemporary US cohort of 58 106 patients who initiated hemodialysis during 1 January 2007-31 December 2011 and survived the first year of dialysis, we observed trends in weight changes during the first year of treatment and then examined the association of post-dialysis weight changes with all-cause mortality.
resultsPatients' post-dialysis weights rapidly decreased and reached a nadir at the 5th month of dialysis with an average decline of 2% from baseline, whereas obese patients (body mass index ≥30 kg/m 2 ) did not reach a nadir and lost ∼3.8% of their weight by the 12th month. Compared with the reference group (-2 to 2% changes in weight), the death hazard ratios (HRs) of patients with -6 to -2% and greater than or equal to -6% weight loss during the first 5 months were 1.08 (95% confidence interval, 1.02-1.14) and 1.14 (1.07-1.22), respectively. Moreover, the death HRs with 2-6% and ≥6% weight gain during the 5th to 12th months were 0.91 (0.85-0.97) and 0.92 (0.86-0.99), respectively.
conclusionsIn patients who survive the first year of hemodialysis, a decline in post-dialysis weight is observed and reaches a nadir at the 5th month. An incrementally larger weight loss during the first 12 months is associated with higher death risk, whereas weight gain is associated with greater survival during the 5th to 12th month but not in the first 5 months of dialysis therapy.
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