ArticleNucleic acids research2017
CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database.
Article in Nucleic acids research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,497 papers.
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Who cites it
1,497 citing papers in PubMed.
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- Integrated genomic and experimental assessment of the biosafety of Paraburkholderia sacchari as a promising microbial chassis.World journal of microbiology & biotechnology · 2026Article
- Antimicrobial Resistance and Genomic Characteristics of ESBL-ProducingAntibiotics (Basel, Switzerland) · 2026Article
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- Whole-Genome Sequencing and Intestinal Metagenome Sequencing Revealed the Carriage and Transmission ofPathogens (Basel, Switzerland) · 2026Article
- Pseudomonas aeruginosa ST4936 with extensive antibacterial drug resistance and virulence determinants from ureteral stent biofilms: whole-genome insights.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Whole-Genome Analysis Reveals Antimicrobial Resistance and Population Structure of Environmental and VeterinaryInternational journal of molecular sciences · 2026Article
- Antimicrobial Resistance and Virulence ofAntibiotics (Basel, Switzerland) · 2026Article
- Global genomic surveillance ofmBio · 2026Article
- Fluoroquinolone-resistantMicrobiology spectrum · 2026Article
- Exploring Safety and Antioxidant Activity of Lactiplantibacillus plantarum F190 and Optimizing Its Exopolysaccharide Production Based on Genomic and In Vitro Experiments.Journal of food science · 2026Article
- High-throughput sequencing dataset of raw and treated wastewater from Jeddah, Saudi Arabia.Data in brief · 2026Article
- Vibrio Community Structure Shapes the Diversity of Carbenicillin-Hydrolysing Class A β-Lactamase Circulating in European Coastal Environments.Environmental microbiology · 2026Article
- Genomic and epidemiological insights into a non-toxigenic Vibrio cholerae O1 Ogawa from an autochthonous case in Brazil.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Detection of an ExPEC-likeBiotech (Basel (Switzerland)) · 2026Article
- Longitudinal investigation of the resistomes in Swedish pig farms.npj antimicrobials and resistance · 2026Article
- Insights into the Mechanisms Driving the Dynamics of Antibiotic Resistance Genes During Pig Manure Composting.Toxics · 2026Article
- SEVA: structural and evolutionary feature integration for predicting virulence factors and antibiotic resistance genes.Microbiome · 2026Article
1,437 more citing papers are in PubMed but not listed here.
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Authors and funding
23 authors.
Funding
Abstract
The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.mcmaster.ca) is a manually curated resource containing high quality reference data on the molecular basis of antimicrobial resistance (AMR), with an emphasis on the genes, proteins and mutations involved in AMR. CARD is ontologically structured, model centric, and spans the breadth of AMR drug classes and resistance mechanisms, including intrinsic, mutation-driven and acquired resistance. It is built upon the Antibiotic Resistance Ontology (ARO), a custom built, interconnected and hierarchical controlled vocabulary allowing advanced data sharing and organization. Its design allows the development of novel genome analysis tools, such as the Resistance Gene Identifier (RGI) for resistome prediction from raw genome sequence. Recent improvements include extensive curation of additional reference sequences and mutations, development of a unique Model Ontology and accompanying AMR detection models to power sequence analysis, new visualization tools, and expansion of the RGI for detection of emergent AMR threats. CARD curation is updated monthly based on an interplay of manual literature curation, computational text mining, and genome analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.