Evidence map›Paper›PMID 27789677›Full record

Trial reportHaematologica2017

Low-dose clofarabine in combination with a standard remission induction in patients aged 18-60 years with previously untreated intermediate and bad-risk acute myeloid leukemia or high-risk myelodysplastic syndrome: combined phase I/II results of the EORTC/GIMEMA AML-14A trial.

Dominik Selleslag, Stefan Suciu, Giovanna Meloni, Petra Muus, Constantijn J M Halkes, Adriano Venditti, Safaa M Ramadan, Hans Pruijt, Liv Meert, Marco Vignetti and 6 more

Open access · goldAbstract readClinical Trial, Phase IClinical Trial, Phase IILetter
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 4 countries.

Dominik SelleslagDepartment of Hematology AZ St-Jan Brugge-Oostende, Belgium.
Stefan SuciuEORTC Headquarters, Brussels, Belgium.
Giovanna MeloniHematology, Sapienza University, Rome, Italy.
Petra MuusDepartment of Hematology, Radboud University, Medical Center, Nijmegen, the Netherlands.
Constantijn J M HalkesDepartment of Hematology, Leiden University Medical Center, the Netherlands.
Adriano VendittiDepartment of Hematology and of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.
Safaa M RamadanEORTC Headquarters, Brussels, Belgium.
Hans PruijtJeroen Bosch Medical Center, Den Bosch, the Netherlands.
Liv MeertEORTC Headquarters, Brussels, Belgium.
Marco VignettiGruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA), Rome, Italy.
Jean-Pierre MarieDepartment of Hematology, Hôpital Saint-Antoine, APHP, Paris, France.
Sébastian WittnebelDepartment of Hematology, Institut Jules Bordet, ULB, Brussels, Belgium.
Theo de WitteDepartment of Tumorimmunology, Radboud University, Medical Center, Nijmegen, the Netherlands.
Sergio AmadoriDepartment of Hematology and of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.
Roelof WillemzeDepartment of Hematology, Leiden University Medical Center, the Netherlands.
Frédéric BaronGIGA-I3-Hematology, University of Liège, Belgium f.baron@ulg.ac.be.
European Organisation for Research and Treatment of Cancer · BELeiden University Medical Center · NLRadboud University Nijmegen · NLUniversity of Rome Tor Vergata · ITAZ Sint-Jan · BEEuropean Institute of Oncology · ITFondazione Gimema Onlus · ITInstitut Jules Bordet · BEJeroen Bosch Ziekenhuis · NLSapienza University of Rome · ITSorbonne Université · FRUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hematopoietic Stem Cell TransplantationAdenine NucleotidesAdolescentAdultAntineoplastic Combined Chemotherapy ProtocolsArabinonucleosidesClofarabineCytarabineDrug Administration ScheduleFemaleGene ExpressionHumansLeukemia, Myeloid, AcuteMaleMiddle AgedMyelodysplastic SyndromesAdenine NucleotidesArabinonucleosidesClofarabineCytarabineOncogene Proteins, Fusion

Identifiers

PMID27789677
PMCPMC5286953
OpenAlexW2626420905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.