ArticleCirculation research2016
Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research.
Abstract readEditorial
In one paragraph
Article in Circulation research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Interstitial cells and arrhythmia.American journal of physiology. Cell physiology · 2026Review
- Shear Stress Conditioning Promotes a Pro-Inflammatory Response in Porcine Endocardial Endothelial Cells.Annals of biomedical engineering · 2025Article
- Article
- Sex differences in cardiac remodeling post myocardial infarction with acute cigarette smoking.Biology of sex differences · 2022Article
- Effects of emodin, a plant-derived anthraquinone, on TGF-β1-induced cardiac fibroblast activation and function.Journal of cellular physiology · 2021Article
- DYNAMIC BIOREACTOR MODEL TO MIMIC EARLY CARDIAC FIBROSIS IN DIABETES.Journal of mechanics in medicine and biology · 2021Article
- Infarct in the Heart: What's MMP-9 Got to Do with It?Biomolecules · 2021Review
- The right ventricular transcriptome signature in Ossabaw swine with cardiometabolic heart failure: implications for the coronary vasculature.Physiological genomics · 2021Article
- Article
- The perpetual sword of Damocles: Cardiac involvement in systemic sclerosis and the role of non-invasive imaging modalities in medical decision making.European journal of rheumatology · 2020Review
- Chronobiological Influence Over Cardiovascular Function: The Good, the Bad, and the Ugly.Circulation research · 2020Review
- Fibrosis in Arrhythmogenic Cardiomyopathy: The Phantom Thread in the Fibro-Adipose Tissue.Frontiers in physiology · 2020Review
- Common pathways and communication between the brain and heart: connecting post-traumatic stress disorder and heart failure.Stress (Amsterdam, Netherlands) · 2019Review
- Platelet-derived growth factor receptor-α is essential for cardiac fibroblast survival.American journal of physiology. Heart and circulatory physiology · 2019Article
- Cardiac Fibrotic Remodeling on a Chip with Dynamic Mechanical Stimulation.Advanced healthcare materials · 2019Article
- Glycoproteomic Profiling Provides Candidate Myocardial Infarction Predictors of Later Progression to Heart Failure.ACS omega · 2019Article
- Multiscale Coupling of an Agent-Based Model of Tissue Fibrosis and a Logic-Based Model of Intracellular Signaling.Frontiers in physiology · 2019Article
- Understanding cardiac extracellular matrix remodeling to develop biomarkers of myocardial infarction outcomes.Matrix biology : journal of the International Society for Matrix Biology · 2019Review
- Utility of Glycosylated TIMP3 molecules: Inhibition of MMPs and TACE to improve cardiac function in rat myocardial infarct model.Pharmacology research & perspectives · 2018Article
- Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts.Journal of the American Heart Association · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Francis G SpinaleFrom the University of South Carolina College of Engineering and Computing, Columbia (F.G.S.); Cardiovascular Translational Research Center (F.G.S.) and Department of Cell Biology and Anatomy (F.G.S.), University of South Carolina School of Medicine, Columbia; WJB Dorn Veteran Affairs Medical Center, Columbia, SC (F.G.S.); Department of Medicine (Cardiology), The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY (N.G.F.); Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, ON, Canada (B.H.); Departments of Biomedical Engineering (J.W.H.) and Medicine (J.W.H.), Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville; Department of Physiology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada (Z.K.); Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson (M.L.L.); and Research Service, G.V. (Sonny) Montgomery Veterans Affairs Medical Center, Jackson, MS (M.L.L.).
Nikolaos G FrangogiannisFrom the University of South Carolina College of Engineering and Computing, Columbia (F.G.S.); Cardiovascular Translational Research Center (F.G.S.) and Department of Cell Biology and Anatomy (F.G.S.), University of South Carolina School of Medicine, Columbia; WJB Dorn Veteran Affairs Medical Center, Columbia, SC (F.G.S.); Department of Medicine (Cardiology), The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY (N.G.F.); Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, ON, Canada (B.H.); Departments of Biomedical Engineering (J.W.H.) and Medicine (J.W.H.), Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville; Department of Physiology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada (Z.K.); Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson (M.L.L.); and Research Service, G.V. (Sonny) Montgomery Veterans Affairs Medical Center, Jackson, MS (M.L.L.).
Boris HinzFrom the University of South Carolina College of Engineering and Computing, Columbia (F.G.S.); Cardiovascular Translational Research Center (F.G.S.) and Department of Cell Biology and Anatomy (F.G.S.), University of South Carolina School of Medicine, Columbia; WJB Dorn Veteran Affairs Medical Center, Columbia, SC (F.G.S.); Department of Medicine (Cardiology), The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY (N.G.F.); Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, ON, Canada (B.H.); Departments of Biomedical Engineering (J.W.H.) and Medicine (J.W.H.), Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville; Department of Physiology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada (Z.K.); Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson (M.L.L.); and Research Service, G.V. (Sonny) Montgomery Veterans Affairs Medical Center, Jackson, MS (M.L.L.).
Jeffrey W HolmesFrom the University of South Carolina College of Engineering and Computing, Columbia (F.G.S.); Cardiovascular Translational Research Center (F.G.S.) and Department of Cell Biology and Anatomy (F.G.S.), University of South Carolina School of Medicine, Columbia; WJB Dorn Veteran Affairs Medical Center, Columbia, SC (F.G.S.); Department of Medicine (Cardiology), The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY (N.G.F.); Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, ON, Canada (B.H.); Departments of Biomedical Engineering (J.W.H.) and Medicine (J.W.H.), Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville; Department of Physiology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada (Z.K.); Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson (M.L.L.); and Research Service, G.V. (Sonny) Montgomery Veterans Affairs Medical Center, Jackson, MS (M.L.L.).
Zamaneh KassiriFrom the University of South Carolina College of Engineering and Computing, Columbia (F.G.S.); Cardiovascular Translational Research Center (F.G.S.) and Department of Cell Biology and Anatomy (F.G.S.), University of South Carolina School of Medicine, Columbia; WJB Dorn Veteran Affairs Medical Center, Columbia, SC (F.G.S.); Department of Medicine (Cardiology), The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY (N.G.F.); Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, ON, Canada (B.H.); Departments of Biomedical Engineering (J.W.H.) and Medicine (J.W.H.), Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville; Department of Physiology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada (Z.K.); Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson (M.L.L.); and Research Service, G.V. (Sonny) Montgomery Veterans Affairs Medical Center, Jackson, MS (M.L.L.).
Merry L LindseyFrom the University of South Carolina College of Engineering and Computing, Columbia (F.G.S.); Cardiovascular Translational Research Center (F.G.S.) and Department of Cell Biology and Anatomy (F.G.S.), University of South Carolina School of Medicine, Columbia; WJB Dorn Veteran Affairs Medical Center, Columbia, SC (F.G.S.); Department of Medicine (Cardiology), The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY (N.G.F.); Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, ON, Canada (B.H.); Departments of Biomedical Engineering (J.W.H.) and Medicine (J.W.H.), Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville; Department of Physiology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada (Z.K.); Department of Physiology and Biophysics, Mississippi Center for Heart Research, University of Mississippi Medical Center, Jackson (M.L.L.); and Research Service, G.V. (Sonny) Montgomery Veterans Affairs Medical Center, Jackson, MS (M.L.L.). mllindsey@umc.edu.
Funding
Chemokines in Healing Myocardial InfarctsR01HL076246 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Nikolaos G Frangogiannis · 2005 to 2026
$9.5MResolution of Inflammation in healing Myocardial InfarctsR01HL085440 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI FRANGOGIANNIS, NIKOLAOS G · 2008 to 2025
$8.5MThe Role of Macrophage-derived MMPs in LV RemodelingR01HL075360 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LINDSEY, MERRY L. · 2004 to 2018
$5.4MMultiscale Models of Cardiac Growth, Remodeling, and Myocardial InfarctionU01HL127654 · NHLBI · UNIVERSITY OF VIRGINIA · PI HOLMES, JEFFREY W · 2015 to 2019
$2.7MLocalized Targeting of Matrix Proteases Following Myocardial InfarctionR01HL111090 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BURDICK, JASON A, SPINALE, FRANCIS G · 2012 to 2015
$2.0MTherapeutic Targeting of Tissue Inhibitor-4 in Hypertrophy and FailureR01HL130972 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI SPINALE, FRANCIS G · 2016 to 2019
$1.9MProteolytic Imaging of Remodeling MyocardiumR42HL131280 · NHLBI · MICRO VIDE, LLC · PI SPINALE, FRANCIS G · 2016 to 2018
$1.8MSystems Biology of Fibroblast Activation Following Myocardial InfarctionR01HL129823 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI LINDSEY, MERRY L. · 2016 to 2019
$1.5MComputational Modeling of Scar Formation After Myocardial InfarctionR01HL116449 · NHLBI · UNIVERSITY OF VIRGINIA · PI HOLMES, JEFFREY W · 2014 to 2018
$1.5MReversal of Myocardial Infarction by Localized StimulationR42HL112519 · NHLBI · MICRO VIDE, LLC · PI SPINALE, FRANCIS G · 2013 to 2015
$1.2MMaladaptive Remodeling in Aging MyocardiumI01BX000168 · VA · VETERANS HEALTH ADMINISTRATION · PI SPINALE, FRANCIS G · 2009 to 2024
–Neutrophil Polarization Following Myocardial InfarctionI01BX000505 · VA · VETERANS HEALTH ADMINISTRATION · PI LINDSEY, MERRY L. · 2009 to 2024
–BLRD VA I01 BX000168BLRD VA I01 BX000505NHLBI NIH HHS R01 HL075360NHLBI NIH HHS R01 HL076246NHLBI NIH HHS R01 HL085440NHLBI NIH HHS R01 HL111090NHLBI NIH HHS R01 HL116449NHLBI NIH HHS R01 HL129823NHLBI NIH HHS R01 HL130972NHLBI NIH HHS R42 HL112519NHLBI NIH HHS R42 HL131280NHLBI NIH HHS U01 HL127654
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsExtracellular MatrixFibroblastsHeart DiseasesHumansMyocardial InfarctionVentricular RemodelingEditorialsextracellular matrixfibroblastmyocardial infarctionmyocardium
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.