Evidence map›Paper›PMID 27789451›Full record

ArticleAJNR. American journal of neuroradiology2017

Endovascular Stroke Treatment of Nonagenarians.

M Möhlenbruch, J Pfaff, S Schönenberger, S Nagel, J Bösel, C Herweh, P Ringleb, M Bendszus, S Stampfl

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Observational
  7. [Acute stroke treatment in old age].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2020
    Review
  8. Article
  9. [Acute stroke treatment in old age].Zeitschrift fur Gerontologie und Geriatrie · 2020
    Article
  10. Article
  11. Review
  12. Article
  13. Retriever first embolectomy (ReFirE): An alternative approach for challenging cervical access.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2017
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M MöhlenbruchFrom the Departments of Neuroradiology (M.M., J.P., C.H., M.B., S. Stampfl).ORCID 0000-0002-5075-704X
J PfaffFrom the Departments of Neuroradiology (M.M., J.P., C.H., M.B., S. Stampfl).ORCID 0000-0003-0672-5718
S SchönenbergerNeurology (S. Schönenberger, S.N., J.B., P.R.), University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0002-3348-6719
S NagelNeurology (S. Schönenberger, S.N., J.B., P.R.), University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0003-2471-6647
J BöselNeurology (S. Schönenberger, S.N., J.B., P.R.), University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0001-5428-0771
C HerwehFrom the Departments of Neuroradiology (M.M., J.P., C.H., M.B., S. Stampfl).ORCID 0000-0002-9223-9662
P RinglebNeurology (S. Schönenberger, S.N., J.B., P.R.), University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0002-5473-8671
M BendszusFrom the Departments of Neuroradiology (M.M., J.P., C.H., M.B., S. Stampfl).ORCID 0000-0002-9094-6769
S StampflFrom the Departments of Neuroradiology (M.M., J.P., C.H., M.B., S. Stampfl) sibylle.stampfl@med.uni-heidelberg.de.ORCID 0000-0003-4358-6112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAlthough endovascular treatment has become a standard therapy in patients with acute stroke, the benefit for very old patients remains uncertain. The purpose of this study was the evaluation of procedural and outcome data of patients ≥90 years undergoing endovascular stroke treatment. MATERIALS AND

methodsWe retrospectively analyzed prospectively collected data of patients ≥90 years in whom endovascular stroke treatment was performed between January 2011 and January 2016. Recanalization was assessed according to the TICI score. The clinical condition was evaluated on admission (NIHSS, prestroke mRS), at discharge (NIHSS), and after 3 months (mRS).

resultsTwenty-nine patients met the inclusion criteria for this analysis. The median prestroke mRS was 2. Successful recanalization (TICI ≥ 2b) was achieved in 22 patients (75.9%). In 9 patients, an NIHSS improvement ≥ 10 points was noted between admission and discharge. After 3 months, 17.2% of the patients had an mRS of 0-2 or exhibited prestroke mRS, and 24.1% achieved mRS 0-3. Mortality rate was 44.8%. There was only 1 minor procedure-related complication (small SAH without clinical sequelae).

conclusionsDespite high mortality rates and only moderate overall outcome, 17.2% of the patients achieved mRS 0-2 or prestroke mRS, and no serious procedure-related complications occurred. Therefore, very high age should not per se be an exclusion criterion for endovascular stroke treatment.

Indexed as

Aged, 80 and overCerebral RevascularizationEndovascular ProceduresFemaleHumansMaleRetrospective StudiesStrokeTreatment Outcome

Identifiers

PMID27789451
PMCPMC7963828

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.