Evidence map›Paper›PMID 27789392›Full record

ReviewMolecular and cellular endocrinology2017

Regulation of body growth by microRNAs.

Julian C Lui

Open access · greenAbstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. [miRNA-26a reduces vascular smooth muscle cell calcification by regulating connective tissue growth factor].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. MiR-149 Aggravates Pyroptosis in Myocardial Ischemia-Reperfusion Damage via Silencing FoxO3.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Julian C LuiSection on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, CRC Rm 1-3330, 10 Center Drive, MSC-1103, Bethesda, MD, 20892-1103, United States. Electronic address: luichunk@mail.nih.gov.
National Institutes of Health · US

Funding

Intramural NIH HHS Z99 HD999999
6 · The paper itself

Abstract

Regulation of body growth remains a fascinating and unresolved biological mystery. One key component of body growth is skeletal and longitudinal bone growth. Children grow taller because their bones grew longer, and the predominant driver of longitudinal bone growth is a cartilaginous structure found near the ends of long bone named the growth plate. Numerous recent studies have started to unveil the importance of microRNAs in regulation of growth plate functions, therefore contributing to regulation of linear growth. In addition to longitudinal growth, other organs in our body need to increase in size and cell number as we grow, and the regulation of organ growth involves both systemic factors like hormones; and other intrinsic mechanisms, which we are just beginning to understand. This review aims to summarize some recent important findings on how microRNAs are involved in both of these processes: the regulation of longitudinal bone growth, and the regulation of organs and overall body growth.

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsBone DevelopmentCartilageChildChondrocytesGrowth HormoneGrowth PlateHumansInsulin-Like Growth Factor ILiverMicroRNAsMuscle, SkeletalOsteogenesisPituitary GlandSignal TransductionGrowth HormoneInsulin-Like Growth Factor IMicroRNAsBody growthBody sizeCartilageGrowth platemiRNA

Identifiers

PMID27789392
PMCPMC7202226
OpenAlexW2536493540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.