Evidence map›Paper›PMID 27788587›Full record

ArticleAIDS care2017

Subjective memory complaints are associated with poorer cognitive performance in adults with HIV.

Asante Kamkwalala, Todd Hulgan, Paul Newhouse

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mechanisms of Cognitive Aging in the HIV-Positive Adult.Current behavioral neuroscience reports · 2017
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Asante Kamkwalalaa Department of Psychiatry , Vanderbilt Center for Cognitive Medicine , Nashville , TN , USA.
Todd Hulganb Department of Medicine, Division of Infectious Diseases , Vanderbilt University Medical Center , Nashville , TN , USA.
Paul Newhousea Department of Psychiatry , Vanderbilt Center for Cognitive Medicine , Nashville , TN , USA.
Geriatric Research Education and Clinical Center · USVanderbilt University · USVanderbilt University Medical Center · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Carolyn Audet · 2015 to 2026
$27.5M
Long-Term Nicotine Treatment of Mild Cognitive Impairment - Bridge FundingR01AG047992 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI AISEN, PAUL S., NEWHOUSE, PAUL A. · 2015 to 2021
$13.4M
NCATS NIH HHS UL1 TR000445NIAID NIH HHS P30 AI110527NIA NIH HHS R01 AG047992
6 · The paper itself

Abstract

With successful antiretroviral therapy in the US, HIV-positive adults now routinely survive into old age. However, increased life expectancy with HIV introduces the added complication of age-related cognitive decline. Aging with HIV has been associated with poorer cognitive outcomes compared to HIV-negative adults. While up to 50% of older HIV-positive adults will develop some degree of cognitive impairment over their lifetime, cognitive symptoms are often not consistently monitored, until those symptoms are significant enough to impair daily life. In this study we found that subjective memory complaint (SMC) ratings correlated with measurable memory performance impairments in HIV-positive adults, but not HIV-negative adults. As the HIV-positive population ages, structured subjective cognitive assessment may be beneficial to identify the early signs of cognitive impairment, and subsequently allow for earlier interventions to maintain cognitive performance as these adults continue to survive into old age.

Indexed as

AdultAgedAgingCognitionCognition DisordersFemaleHIV InfectionsHumansMaleMemory DisordersMemory, Short-TermMiddle AgedNeuropsychological TestsTask Performance and AnalysisYoung AdultagingcognitionHIV-1memorysubjective memory impairment

Identifiers

PMID27788587
PMCPMC5584557
OpenAlexW2542507609

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.