ArticlePloS one2016
Microorganisms Causing Community-Acquired Acute Bronchitis: The Role of Bacterial Infection.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- HL301 in the treatment of acute bronchitis: a phase 2b, randomized, double-blind, placebocontrolled, multicenter study.The Korean journal of internal medicine · 2020Trial
- Aerobic bacteria study, clinical spectrum, and outcome of patients with community-acquired multidrug-resistant pathogens.Journal of family medicine and primary care · 2024Article
- Investigation into the Effectiveness of an Herbal Combination (AngocinAntibiotics (Basel, Switzerland) · 2024Article
- Chlamydophila pneumoniae-associated community-acquired pneumonia in paediatric patients of a tertiary care hospital in Mexico: molecular diagnostic and clinical insights.Scientific reports · 2023Article
- Drivers of respiratory health care demand in Acre state, Brazilian Amazon: a cross-sectional study.BMC public health · 2022Review
- Article
- Focus of infection and microbiological etiology in community-acquired infections in hospitalized adult patients in the Faroe Islands.BMC infectious diseases · 2019Observational
- Validation of discharge diagnosis codes to identify serious infections among middle age and older adults.BMJ open · 2018Article
- Phage therapy in the management of respiratory and pulmonary infections: a systematic review.Therapeutic advances in infectious diseaseReview
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough acute bronchitis is quite common, there is relatively limited information regarding the microorganisms that are involved in this illness.
methodsWe performed a prospective study of acute bronchitis at 31 hospitals and clinics in Korea from July 2011 to June 2012. Sputum specimens were collected for polymerase chain reaction (PCR) and culture of microorganisms.
resultsOf the 811 enrolled patients, 291 had acceptable sputum specimens that were included for analysis of the etiologic distribution. With multiplex PCR testing, viruses were identified in 36.1% (105/291), most commonly rhinovirus (25.8%) and coronavirus (3.8%). Typical bacteria were isolated in 126/291 (43.3%) patients. Among these patients Haemophilus influenzae (n = 39) and Streptococcus pneumoniae (n = 30) were isolated most commonly; atypical bacteria were identified in 44 (15.1%) patients. Bacteria-only, virus-only, and mixed infections (bacteria plus virus) accounted for 36.7% (98/291), 17.2% (50/291), and 18.9% (55/291) of infections, respectively. In particular, 52.4% of patients with viral infection had a concurrent bacterial infection, and rhinovirus was the most common virus in mixed infections (40/55). Additionally, infections with typical bacteria were more common in patients with chronic lung disease (p = 0.029), and typical bacterial infections showed a trend towards a higher prevalence with older age (p = 0.001).
conclusionsBacteria were associated with almost half of community-acquired acute bronchitis cases. Additional studies are required to further illuminate the role of bacteria and to identify patient groups most likely to benefit from antibiotic treatment.
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