ArticlePloS one2016
Loss-of-Function Mutations in Three Homoeologous PHYTOCLOCK 1 Genes in Common Wheat Are Associated with the Extra-Early Flowering Phenotype.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 56 citations in OpenAlex.
- Current status and future perspective of genomics-assisted breeding in wheat (Breeding science · 2026Article
- Population-scale gene expression analysis reveals the contribution of expression diversity to the modern wheat improvement.Nature communications · 2025Article
- Genetic mapping and haplotype analysis identify novel candidate genes for high night temperature tolerance in winter wheat.The plant genome · 2025Article
- Ambient temperature influenced co-expression network of major developmental, circadian, and photoreceptor genes in bread wheat.Scientific reports · 2025Article
- Phenotypic plasticity of flowering time and plant height related traits in wheat.BMC plant biology · 2025Article
- Molecular genetic regulation of the vegetative-generative transition in wheat from an environmental perspective.Annals of botany · 2025Review
- Chromatin loops gather targets of upstream regulators together for efficient gene transcription regulation during vernalization in wheat.Genome biology · 2024Article
- Identification of the causal mutation in early heading mutant of bread wheat (Molecular breeding : new strategies in plant improvement · 2024Article
- Epigenetic control on transcription of vernalization genes and whole-genome gene expression profile induced by vernalization in common wheat.Plant diversity · 2024Article
- From Images to Loci: Applying 3D Deep Learning to Enable Multivariate and Multitemporal Digital Phenotyping and Mapping the Genetics Underlying Nitrogen Use Efficiency in Wheat.Plant phenomics (Washington, D.C.) · 2024Article
- Phytochromes transmit photoperiod information via the evening complex in Brachypodium.Genome biology · 2023Article
- Natural variations of wheat EARLY FLOWERING 3 highlight their contributions to local adaptation through fine-tuning of heading time.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- PHYTOCHROME C regulation of photoperiodic flowering via PHOTOPERIOD1 is mediated by EARLY FLOWERING 3 in Brachypodium distachyon.PLoS genetics · 2023Article
- EARLY FLOWERING 3 interactions with PHYTOCHROME B and PHOTOPERIOD1 are critical for the photoperiodic regulation of wheat heading time.PLoS genetics · 2023Article
- Identification of structural variations related to drought tolerance in wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Wheat EARLY FLOWERING 3 affects heading date without disrupting circadian oscillations.Plant physiology · 2023Article
- Allelic variations ofBreeding science · 2022Article
- Plant clock modifications for adapting flowering time to local environments.Plant physiology · 2022Article
- Time-to-Collision Estimations in Young Drivers with Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder.Journal of autism and developmental disorders · 2022Article
- Functional characterization of genes with daily expression patterns in common wheat.Plant molecular biology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Triticum aestivum L. cv 'Chogokuwase' is an extra-early flowering common wheat cultivar that is insensitive to photoperiod conferred by the photoperiod insensitive alleles at the Photoperiod-B1 (Ppd-B1) and Ppd-D1loci, and does not require vernalization for flowering. This reduced vernalization requirement is likely due to the spring habitat allele Vrn-D1 at the VERNALIZATION-D1 locus. Genotypes of the Ppd-1 loci that determine photoperiod sensitivity do not fully explain the insensitivity to photoperiod seen in 'Chogokuwase'. We detected altered expression patterns of clock and clock-output genes including Ppd-1 in 'Chogokuwase' that were similar to those in an einkorn wheat mutant that lacks the clock-gene homologue, wheat PHYTOCLOCK 1 (WPCL1). Presumptive loss-of-function mutations in all WPCL1 homoeologous genes were found in 'Chogokuwase' and 'Geurumil', one of the parental cultivars. Segregation analysis of the two intervarietal F2 populations revealed that all the examined F2 plants that headed as early as 'Chogokuwase' had the loss-of-function wpcl1 alleles at all three homoeoloci. Some F2 plants carrying the wpcl1 alleles at three homoeoloci headed later than 'Chogokuwase', suggesting the presence of other loci influencing heading date. Flowering repressor Vrn-2 was up-regulated in 'Chogokuwase' and 'Geurumil' that had the triple recessive wpcl1 alleles. An elevated transcript abundance of Vrn-2 could explain the observation that 'Geurumil' and some F2 plants carrying the three recessive wpcl1 homeoealleles headed later than 'Chogokuwase'. In spite of the up-regulation of Vrn-2, 'Chogokuwase' may have headed earlier due to unidentified earliness genes. Our observations indicated that loss-of-function mutations in the clock gene wpcl1 are necessary but are not sufficient to explain the extra-early heading of 'Chogokuwase'.
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