ArticlePloS one2016
Effect of Environmental Factors on Low Weight in Non-Premature Births: A Time Series Analysis.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Adverse Birth Outcomes Related to NOInternational journal of environmental research and public health · 2020Pooled it
- A comprehensive evaluation of the association between ambient air pollution and adverse health outcomes of major organ systems: a systematic review with a worldwide approach.Environmental science and pollution research international · 2019Pooled it
- WHO Environmental Noise Guidelines for the European Region: A Systematic Review on Environmental Noise and Adverse Birth Outcomes.International journal of environmental research and public health · 2017Pooled it
- Heat Exposure and Maternal Health in the Face of Climate Change.International journal of environmental research and public health · 2017Pooled it
- Vector-borne infectious diseases in pregnancy in the era of climate change: A focus on mosquito- and tick-borne pathogens (Review).Experimental and therapeutic medicine · 2025Review
- Impact of Climate Change on Reproductive Health and Pregnancy Outcomes: A Systematic Review.Cureus · 2024Review
- Ambient climatic factors and term birthweight: A study of critical windows of exposure in the Republic of Cyprus.Environmental research · 2023Article
- The influence of air pollution on gestational age at delivery and birthweight in patients with or without respiratory allergy: A nested case-control study.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Decreased birth weight after prenatal exposure to wildfires on the eastern coast of Korea in 2000.Epidemiology and health · 2023Article
- Relationship between birth weight and ambient temperature during pregnancy in a cross-sectional study of the residents of Suzhou, China.Frontiers in public health · 2023Article
- Extreme Heat and Pregnancy Outcomes: A Scoping Review of the Epidemiological Evidence.International journal of environmental research and public health · 2022Article
- The effect of prenatal temperature and PMEnvironment international · 2021Article
- Placental gene networks at the interface between maternal PMEnvironmental research · 2021Article
- Association between moderated level of air pollution and fetal growth: the potential role of noise exposure.Scientific reports · 2021Article
- Assessing the effectiveness of vehicle emission regulations on improving perinatal health: a population-based accountability study.International journal of epidemiology · 2021Article
- Estimating the Combined Effects of Natural and Built Environmental Exposures on Birthweight among Urban Residents in Massachusetts.International journal of environmental research and public health · 2020Article
- Impacts of high temperature on adverse birth outcomes in Seoul, Korea: Disparities by individual- and community-level characteristics.Environmental research · 2019Article
- Associations between ambient air temperature, low birth weight and small for gestational age in term neonates in southern Israel.Environmental health : a global access science source · 2018Article
- Industrial air pollution and low birth weight: a case-control study in Texas, USA.Environmental science and pollution research international · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveExposure to pollutants during pregnancy has been related to adverse birth outcomes. LBW can give rise to lifelong impairments. Prematurity is the leading cause of LBW, yet few studies have attempted to analyse how environmental factors can influence LBW in infants who are not premature. This study therefore sought to analyse the influence of air pollution, noise levels and temperature on LBW in non-premature births in Madrid during the period 2001-2009.
methodsEcological time-series study to assess the impact of PM2.5, NO2 and O3 concentrations, noise levels, and temperatures on LBW among non-premature infants across the period 2001-2009. Our analysis extended to infants having birth weights of 1,500 g to 2,500 g (VLBW) and less than 1,500 g (ELBW). Environmental variables were lagged until 37 weeks with respect to the date of birth, and cross-correlation functions were used to identify explaining lags. Results were quantified using Poisson regression models.
resultsAcross the study period 298,705 births were registered in Madrid, 3,290 of which had LBW; of this latter total, 1,492 were non-premature. PM2.5 was the only pollutant to show an association with the three variables of LBW in non-premature births. This association occurred at around the third month of gestation for LBW and VLBW (LBW: lag 23 and VLBW: lag 25), and at around the eighth month of gestation for ELBW (lag 6). Leqd was linked to LBW at lag zero. The RR of PM2.5 on LBW was 1.01 (1.00 1.03). The RR of Leqd on LBW was 1.09 (0.99 1.19)(p<0.1).
conclusionsThe results obtained indicate that PM2.5 had influence on LBW. The adoption of measures aimed at reducing the number of vehicles would serve to lower pregnant women's exposure. In the case of noise should be limited the exposure to high levels during the final weeks of pregnancy.
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Registered trials
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