Evidence map›Paper›PMID 27788135›Full record

ReviewPLoS neglected tropical diseases2016

Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings.

Robert J Shorten, Colin S Brown, Michael Jacobs, Simon Rattenbury, Andrew J Simpson, Stephen Mepham

Open access · goldAbstract readReview
In one paragraph

Review in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Ebola Virus IgG Seroprevalence in Southern Mali.Emerging infectious diseases · 2021
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. The Crux of Ebola Diagnostics.The Journal of infectious diseases · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Robert J ShortenPublic Health Laboratory Manchester, Manchester Royal Infirmary, Manchester, United Kingdom.
Colin S BrownHospital for Tropical Diseases, University College London Hospital, London, United Kingdom.
Michael JacobsDepartment of Infection, Royal Free London NHS Foundation Trust, London, United Kingdom.
Simon RattenburyDepartment of Infection, Royal Free London NHS Foundation Trust, London, United Kingdom.
Andrew J SimpsonUniversity College London, Centre for Clinical Microbiology, Department of Infection, London United Kingdom.
Stephen MephamDepartment of Infection, Royal Free London NHS Foundation Trust, London, United Kingdom.
Royal Free London NHS Foundation Trust · GBManchester Royal Infirmary · GBPublic Health England · GBRoyal London Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Ebola virus disease (EVD) outbreak in West Africa was unprecedented in scale and location. Limited access to both diagnostic and supportive pathology assays in both resource-rich and resource-limited settings had a detrimental effect on the identification and isolation of cases as well as individual patient management. Limited access to such assays in resource-rich settings resulted in delays in differentiating EVD from other illnesses in returning travellers, in turn utilising valuable resources until a diagnosis could be made. This had a much greater impact in West Africa, where it contributed to the initial failure to contain the outbreak. This review explores diagnostic assays of use in EVD in both resource-rich and resource-limited settings, including their respective limitations, and some novel assays and approaches that may be of use in future outbreaks.

Indexed as

Africa, WesternEbolavirusHemorrhagic Fever, EbolaHumansTravel

Identifiers

PMID27788135
PMCPMC5082928
OpenAlexW2544710797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.