Evidence map›Paper›PMID 27787746›Full record

ArticleInternational journal of hematology2017

Outcome differences between children and adolescents and young adults with non-Hodgkin lymphoma following stem cell transplantation.

Ryoji Kobayashi, Tetsuo Mitsui, Naoto Fujita, Tomoo Osumi, Tomohiro Aoki, Kazunari Aoki, Ritsuro Suzuki, Takahiro Fukuda, Toshihiro Miyamoto, Koji Kato and 13 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Quality-of-Life Trajectories in Adolescent and Young Adult versus Older Adult Allogeneic Hematopoietic Cell Transplantation Recipients.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Ryoji KobayashiDepartment of Pediatrics, Sapporo Hokuyu Hospital, Higashi-Sapporo 6-6, Shiroishiku, Sapporo, Hokkaido, 003-0006, Japan. r-koba@jacls.jp.
Tetsuo MitsuiDepartment of Pediatrics, Yamagata University School of Medicine, Yamagata, Japan.
Naoto FujitaDepartment of Pediatrics, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan.
Tomoo OsumiChildren's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
Tomohiro AokiDepartment of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kazunari AokiDepartment of Hematology and Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ritsuro SuzukiShimane University Hospital Cancer Center, Oncology/Hematology, Izumo, Japan.
Takahiro FukudaDivision of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Toshihiro MiyamotoMedicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Koji KatoDepartment of Hematology and Oncology, Children's Medical Center, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan.
Hirohisa NakamaeHematology, Osaka City University Hospital, Osaka, Japan.
Hiroaki GotoDivision of Hemato-oncology/Regenerative Medicine, Kanagawa Children's Medical Center, Yokohama, Japan.
Tetsuya EtoDepartment of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
Masami InoueDepartment of Hematology/Oncology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Takehiko MoriDivision of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Kiminori TeruiDepartment of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Masahito OnizukaDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Japan.
Katsuyoshi KohDepartment of Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan.
Yuhki KogaDepartment of Pediatrics, Kyushu University Hospital, Fukuoka, Japan.
Tatsuo IchinoheDepartment of Hematology and Oncology, Hiroshima University Hospital, Hiroshima, Japan.
Akihisa SawadaDepartment of Hematology/Oncology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Yoshiko AtsutaJapanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan.
Junji SuzumiyaShimane University Hospital Cancer Center, Oncology/Hematology, Izumo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies of patients with acute lymphoblastic leukemia and acute myeloid leukemia who received stem cell transplantation (SCT) have reported that adolescents and young adults (AYAs) experience higher transplant-related mortality than that in younger children. However, to the best of our knowledge, there have been no reports of a similar comparison of non-Hodgkin lymphoma (NHL) patients who received SCT. We analyzed 918 patients aged 30 years and younger who received their first stem cell transplantation for NHL. Of the allogeneic transplant patients, children and AYAs did not significantly differ in survival rate, event-free survival rate, relapse rate, or transplant-related mortality. However, 5-year transplant-related mortality after autologous transplantation was significantly higher in children than in AYAs (5.1% in children vs. 0.8% in AYAs, P = 0.0043). The cause of transplant-related death in three of four children was interstitial pneumonitis. In NHL patients, transplantation results in AYAs were not inferior than those in children.

Indexed as

AdolescentAdultAge FactorsAllograftsAutograftsChildChild, PreschoolFemaleHumansInfantInfant, NewbornLymphoma, Non-HodgkinMalePneumoniaStem Cell TransplantationSurvival RateAYANon-Hodgkin lymphomaStem cell transplantation

Identifiers

PMID27787746

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.