Evidence map›Paper›PMID 27787342›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2017

Conditional Cash Transfers Improve Retention in PMTCT Services by Mitigating the Negative Effect of Not Having Money to Come to the Clinic.

Marcel Yotebieng, Kathryn E Moracco, Harsha Thirumurthy, Andrew Edmonds, Martine Tabala, Bienvenu Kawende, Landry K Wenzi, Emile W Okitolonda, Frieda Behets

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01838005 (Conditional Cash Transfers to Increase Uptake of and Retention of PMTCT Services), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01838005 nacompletednot on this map

Conditional Cash Transfers to Increase Uptake of and Retention of PMTCT Services

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2013 to 2015Enrolled433ConditionsHIVArmsConditional cash transfer
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Marcel Yotebieng*Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH; Departments of †Epidemiology; ‡Health Behavior; §Health Policy and Management, The University of North Carolina at Chapel Hill, Chapel Hill, NC; ‖School of Public Health, The University of Kinshasa, Kinshasa, Democratic Republic of Congo; and ¶Department of Social Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Kathryn E Moracco
Harsha Thirumurthy
Andrew Edmonds
Martine Tabala
Bienvenu Kawende
Landry K Wenzi
Emile W Okitolonda
Frieda Behets
University of Kinshasa · CDUniversity of North Carolina at Chapel Hill · USThe Ohio State University · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Long term outcomes of therapy in women initiated on lifelong ART because of pregnancy in DR CongoR01HD087993 · NICHD · OHIO STATE UNIVERSITY · PI BABAKAZO, PELAGIE DIAMBALULA, YOTEBIENG, MARCEL · 2016 to 2020
$3.1M
Conditional cash transfers to increase uptake of and retention of PMTCT servicesR01HD075171 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YOTEBIENG, MARCEL · 2012 to 2013
$778k
NIAID NIH HHS P30 AI050410NIAID NIH HHS U01 AI096299NICHD NIH HHS P2C HD050924NICHD NIH HHS R01 HD075171NICHD NIH HHS R01 HD087993
6 · The paper itself

Abstract

objectiveTo elucidate the mechanisms by which a cash incentive intervention increases retention in prevention of mother-to-child transmission services.

methodsWe used data from a randomized controlled trial in Kinshasa, Democratic Republic of Congo. Perceptual factors associated with loss to follow-up (LTFU) through 6 weeks postpartum were first identified. Then, binomial models were used to assess interactions between LTFU and identified factors, and the cash incentive intervention.

resultsParticipants were less likely to be LTFU if they perceived HIV as a "very serious" health problem for their baby vs. not [risk difference (RD), -0.13; 95% confidence interval (CI): -0.30 to 0.04], if they believed it would be "very likely" to pass HIV to their baby if they did not take any HIV drug vs. not (RD, -0.15; 95% CI: -0.32 to 0.02), and if they anticipated that not having money would make it difficult for them to come to the clinic vs. not (RD, 0.12; 95% CI: -0.07 to 0.30). The effect of each of the 3 factors on LTFU was antagonistic to that of receiving the cash incentive intervention. The excess risk due to interaction between the cash incentive intervention and the anticipated difficulty of "not having money" to come to the clinic was exactly equal to the effect of removing this perceived barrier (excess risk due to interaction, -0.12; 95% CI: -0.35 to 0.10).

conclusionsOur analyses show that cash transfers improve retention in prevention of mother-to-child transmission services mainly by mitigating the negative effect of not having money to come to the clinic.

Indexed as

Medication AdherenceMotivationDemocratic Republic of the CongoFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalPregnancy

Identifiers

PMID27787342
PMCPMC5268132
OpenAlexW2545148820

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.