Evidence map›Paper›PMID 27786275›Full record

ArticleNature communications2016

Evaluating frequency and quality of pathogen-specific T cells.

Nadia Anikeeva, Dolores Grosso, Neal Flomenberg, Yuri Sykulev

Abstract read
In one paragraph

Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Microfluidic T Cell Selection by Cellular Avidity.Advanced healthcare materials · 2022
    Article
  4. A review of vaccine effects on women in light of the COVID-19 pandemic.Taiwanese journal of obstetrics & gynecology · 2020
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nadia AnikeevaDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Dolores GrossoDepartment of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Neal FlomenbergDepartment of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Yuri SykulevDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

Funding

X-Ray Crystallography and Macromolecular CharacterizationP30CA056036 · NCI · THOMAS JEFFERSON UNIVERSITY · PI Andrew Chapman · 1995 to 2026
$94.8M
NCI NIH HHS P30 CA056036
6 · The paper itself

Abstract

It is generally accepted that enumeration and characterization of antigen-specific T cells provide essential information about potency of the immune response. Here, we report a new technique to determine the frequency and potency of antigen-specific CD8 T cells. The assay measures changes of intracellular Ca

Indexed as

Antigens, ViralCalciumCD8-Positive T-LymphocytesCytomegalovirusCytomegalovirus InfectionsEnzyme-Linked Immunospot AssayHost-Pathogen InteractionsHumansInterferon-gammaStem Cell TransplantationAntigens, ViralCalciumInterferon-gamma

Identifiers

PMID27786275
PMCPMC5095286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.