Evidence map›Paper›PMID 27785565›Full record

ArticleEuropean journal of nutrition2018

Durum wheat particle size affects starch and protein digestion in vitro.

Giuseppina Mandalari, Zara Merali, Peter Ryden, Simona Chessa, Carlo Bisignano, Davide Barreca, Ersilia Bellocco, Giuseppina Laganà, Richard M Faulks, Keith W Waldron

Abstract read
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In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Giuseppina MandalariThe Model Gut, Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Zara MeraliThe Biorefinery Centre, Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Peter RydenThe Biorefinery Centre, Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Simona ChessaThe Model Gut, Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Carlo BisignanoDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, University of Messina, Sal. Sperone 31, 98166, Messina, Italy.
Davide BarrecaDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, University of Messina, Sal. Sperone 31, 98166, Messina, Italy.
Ersilia BelloccoDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, University of Messina, Sal. Sperone 31, 98166, Messina, Italy.
Giuseppina LaganàDipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, University of Messina, Sal. Sperone 31, 98166, Messina, Italy.
Richard M FaulksThe Model Gut, Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK.
Keith W WaldronThe Biorefinery Centre, Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK. keith.waldron@ifr.ac.uk.
Quadram Institute · GBUniversity of Messina · ITNorwich Research Park · GB

Funding

Biotechnology and Biological Sciences Research Council BB/H004866/1Biotechnology and Biological Sciences Research Council BB/H004874/1
6 · The paper itself

Abstract

purposeThe term bioaccessibility refers to the proportion of a nutrient released from a complex food matrix during digestion and, therefore, becoming potentially available for absorption in the gastrointestinal tract. In the present study, we assessed the starch and protein bioaccessibility from a range of wheat endosperm products differing in particle size.

methodsFive porridge meals (size A, flour, mean particle size 0.11 mm, size B, small, mean particle size 0.38 mm, size C, semolina, mean particle size 1.01 mm, size D, medium, mean particle size 1.44 mm, size E, large, mean particle size 1.95 mm) with theoretically different postprandial glycaemic responses were subjected to oral processing in vitro, followed by simulated gastric and duodenal digestion.

resultsA significant increase (P < 0.001) in starch degradation was observed in size A (52%) compared with size E (25%). Both sizes C and D gave less, although not significantly, digestible starch (32 and 28%, respectively). The glucose release significantly decreased as the particle size of the meal increased (92.16% detected for size A vs 47.39% for size E). In agreement with starch degradation and glucose release, size A gave the most digestible protein.

conclusionsThis data provide further evidence that, by decreasing the size of wheat endosperm, starch release and glycaemic response are enhanced. We also showed that protein bioaccessibility followed a similar trend as for starch digestion. Finally, these results support the hypothesis that different degrees of starch encapsulation elicit different blood glucose responses.

Indexed as

DigestionParticle SizeTriticumAmylasesBileBiological AvailabilityBlood GlucoseDuodenumEdible GrainGastric MucosaGlucoseHumansLipasePancreasPepsin APlant ProteinsAmylasesBlood GlucoseGlucoseLipasePepsin APlant ProteinsStarchGlycaemic responseIn vitro modelsStarch digestionWheat endosperm

Identifiers

PMID27785565
OpenAlexW2545260886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.