Evidence map›Paper›PMID 27785535›Full record

ReviewHNO2016

[Conversion of sound into auditory nerve action potentials].

J Encke, J Kreh, F Völk, W Hemmert

Abstract readReview
PubMed Publisher
In one paragraph

Review in HNO, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

J EnckeBioanaloge Informationsverarbeitung, Zentralinstitut für Medizintechnik, Technische Universität München, Boltzmannstr. 11, 85748, Garching, Deutschland.
J KrehBioanaloge Informationsverarbeitung, Zentralinstitut für Medizintechnik, Technische Universität München, Boltzmannstr. 11, 85748, Garching, Deutschland.
F VölkBioanaloge Informationsverarbeitung, Zentralinstitut für Medizintechnik, Technische Universität München, Boltzmannstr. 11, 85748, Garching, Deutschland.
W HemmertBioanaloge Informationsverarbeitung, Zentralinstitut für Medizintechnik, Technische Universität München, Boltzmannstr. 11, 85748, Garching, Deutschland. werner.hemmert@tum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outer hair cells play a major role in the hearing process: they amplify the motion of the basilar membrane up to a 1000-fold and at the same time sharpen the excitation patterns. These patterns are converted by inner hair cells into action potentials of the auditory nerve. Outer hair cells are delicate structures and easily damaged, e. g., by overexposure to noise. Hearing aids can amplify the amplitude of the excitation patterns, but they cannot restore their degraded frequency selectivity. Noise overexposure also leads to delayed degeneration of auditory nerve fibers, particularly those with low a spontaneous rate, which are important for the coding of sound in noise. However, this loss cannot be diagnosed by pure-tone audiometry.

Indexed as

Acoustic StimulationAction PotentialsAnimalsCochlear NerveEvoked Potentials, AuditoryHair Cells, Auditory, OuterHearingHumansMechanotransduction, CellularModels, NeurologicalAuditory perceptionCochlear hair cellsComputer modelsHearing lossInner ear

Identifiers

PMID27785535

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.