ArticlePreventive medicine reports2016
Physical activity and long-term mortality risk in older adults: A prospective population based study (NEDICES).
Article in Preventive medicine reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Procedural Pattern, Clinical Outcomes, and Cost Analysis of Transcatheter Aortic Valve Replacement in Korea.JACC. Asia · 2026Article
- Effect of type-2 diabetes mellitus in long-term mortality in older adults: The NEDICES cohort study.Diabetes research and clinical practice · 2025Review
- Long-term exercise training and inflammatory biomarkers in healthy subjects: a meta-analysis of randomized controlled trials.Frontiers in psychology · 2023Review
- Effects of physical exercise on biomarkers of oxidative stress in healthy subjects: A meta-analysis of randomized controlled trials.Open life sciences · 2023Article
- Association between physical activity and risk of renal function decline and mortality in community-dwelling older adults: a nationwide population-based cohort study.BMC geriatrics · 2022Article
- The health status: the ignored risk factor in dementia incidence. NEDICES cohort.Aging clinical and experimental research · 2022Article
- Aerobic Exercise Attenuates Frailty in Aging Male and Female C57Bl/6 Mice and Effects Systemic Cytokines Differentially by Sex.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Physical activity and risk of Parkinson's disease and parkinsonism in a prospective population-based study (NEDICES).Preventive medicine reports · 2021Article
- Physical Activity and Cumulative Long-Term Care Cost among Older Japanese Adults: A Prospective Study in JAGES.International journal of environmental research and public health · 2021Article
- Lifestyle in the Very Elderly Matters.Arquivos brasileiros de cardiologia · 2020Article
- Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs.Biochimica et biophysica acta. Molecular basis of disease · 2020Review
- Cross-cultural Adaptation and Psychometric Properties of the Arabic Version of the Rapid Assessment of Physical Activity.Oman medical journal · 2020Article
- Effects of Physical Exercises and Verbal Stimulation on the Functional Efficiency and Use of Free Time in an Older Population under Institutional Care: A Randomized Controlled Trial.Journal of clinical medicine · 2020Article
- Physical Exercise Potentials Against Viral Diseases Like COVID-19 in the Elderly.Frontiers in medicine · 2020Article
- Prescribing Physical Activity for the Prevention and Treatment of Osteoporosis in Older Adults.Healthcare (Basel, Switzerland) · 2017Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To analyze whether Physical activity (PA) reduces mortality risk at thirteen years' follow-up in a population-based cohort of Spanish older adults. The NEDICES (Neurological Disorders in Central Spain) is a prospective population-based survey of older adults (age ≥ 65 years) that comprised 5278 participants at baseline. A modified version of the Rosow-Breslau questionnaire was applied to categorize the PA (sedentary, light, moderate and high) and dates of death were collected from the Official Spanish Death Registry. Cox regression models adjusted for different covariates (age, sex, marital status, smoking, previous stroke, Parkinson disease, incident dementia, body mass index, comorbidity indexes and functional assessment) were used to evaluate the hazard of death at thirteen years' interval according to different levels of PA. 1710 deaths (52.9% men vs. 47.1% women) were identified among 3633 individuals at thirteen years' follow-up. Hazard ratios (HRs) of the light, moderate, and high PA groups (vs. sedentary group) were 0.64 (95% confidence interval (CI) [0.56, 0.72], p < 0.001), 0.61 (95% CI [0.53, 0.70], p < 0.001) and 0.48 (95% CI [0.41, 0.55], p < 0.001), respectively. Significant dose effects were observed between light versus the sedentary group and intense versus the moderate group. PA prevents long-term mortality in older Spanish adults, with the highest intensity levels being those related to the lowest risk of mortality. These findings indicate that health policies for old age care should include PA as one of the main targets.
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