ArticleGastroenterology research2014
Timing of Pharyngeal Swallow Events in Chagas' Disease.
Article in Gastroenterology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Cross-Sectional Study of Swallowing Phases in Cases of Megaesophagus Caused by Chagas Disease.Gastroenterology research · 2021Article
- How does per-oral endoscopic myotomy compare to Heller myotomy? The Latin American perspective.Endoscopy international open · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEsophageal involvement by Chagas' disease causes a significative decrease in the number of neurons of the esophageal myenteric plexus, causing an impairment of esophageal motility with the same alterations described in primary esophageal achalasia. There is also a longer duration of pharyngeal transit, which might be consequent of the involvement of the central control of swallowing by the disease, or an adaptation of the pharynx to the difficult bolus transit through the esophagus, which could contribute to the complaint of dysphagia.
methodsWe studied, by videofluoroscopy, the sequence and timings of pharyngeal bolus transit in 16 patients with esophageal involvement by Chagas' disease and 12 healthy volunteers. Each subject swallowed in duplicate 5 mL and 10 mL of liquid and paste boluses.
resultsThere was no difference between Chagas' disease patients and normal volunteers in the sequence and timing of events associated with pharyngeal bolus flow, for liquid and paste boluses, and for 5 mL and 10 mL.
conclusionThe timing and sequence of swallow pharyngeal events of patients with Chagas' disease do not differ from that of control subjects, which suggested that the central control of swallowing is not impaired by the disease.
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